CDN 1163 - CAS 892711-75-0
Category: Inhibitor
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Molecular Formula:
C20H20N2O2
Molecular Weight:
320.38
COA:
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Targets:
Others
Description:
CDN 1163 is an allosteric activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2), increasing Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. It reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. CDN 1163 has the potential to treat type-2 diabetes and metabolic dysfunction.
Brife Description:
SERCA2 activator
Purity:
≥98% by HPLC
Synonyms:
CDN-1163; CDN 1163; CDN1163; 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide; 4-Isopropoxy-N-(2-methylquinolin-8-yl)benzamide
MSDS:
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InChIKey:
GVGVYDCVFBGALZ-UHFFFAOYSA-N
InChI:
InChI=1S/C20H20N2O2/c1-13(2)24-17-11-9-16(10-12-17)20(23)22-18-6-4-5-15-8-7-14(3)21-19(15)18/h4-13H,1-3H3,(H,22,23)
Canonical SMILES:
CC1=NC2=C(C=CC=C2NC(=O)C3=CC=C(C=C3)OC(C)C)C=C1
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Chemical Structure

CAS 892711-75-0 CDN 1163

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