|Description||CDK2, a member of the eukaryotic S/T protein kinase family, catalyzes the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. Activity of CDK2 is maximal during S phase and G2; activated by interaction with cyclin E during the early stages of DNA synthesis to permit G1-S transition, and subsequently activated by cyclin A2 (cyclin A1 in germ cells) during the late stages of DNA replication to drive the transition from S phase to mitosis, the G2 phase.|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
BMS-188494 is the prodrug of BMS-187745, a squalene synthase inhibitor used as an anticholesterol drug.
FR-900490 is a new type of immunoactive substance isolated from Disocia sp. F-11809. It is effective in reversing the damage to bone marrow caused by mitomycin ...
JTE-013 is a Potent and selective sphingosine-1-phosphate (S1P) receptor 2 (S1P2) antagonist (IC50=17.6 nM).
Neurotensin (8-13), the smallest active fragment of neurotensin, results in a decrease in cell-surface NT1 receptors (NTR1) density.
Etretinate is a second-generation retinoid to treat severe psoriasis. It has been replaced by acitretin, a safer metabolite of etretinate.
Benzoylmesaconine is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis.
Ginsenoside Re, extracted from the traditional Chinese herb ginseng, responsible for some of the pharmacological functions.
Yunaconitine is a highly toxic aconitum alkaloid.
AD80, also called as A-196, is a multikinase inhibitor that inhibits against human BRAF, S6K, and SRC and shows strong activity against RET inhibitor.
FR-218944 is a vasopressin antagonist compound.
This active molecular, also known as GSK-557296B is a selective, sub-nanomolar (Ki=0.13 nM) oxytocin receptor antagonist with more than 30000-fold selectivity o...
BMS-363131 is very potent inhibitor of human tryptase with inhibitory activity against bovine trypsin
TPY-5628, a pyrrole derivative, has been found to be commonly used in sorts of chemical areas like anticancer drugs as an significant intermediate.
Creatinine is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.
PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) and derivative of...
A potent and selective inhibitor of E-selectin (IC50= 7 nM) and ICAM-1 (IC50= 5 nM)
Ciraparantag, also called as PER977, a synthetic, cationic small molecule, has potential to be a simple, inexpensive universal anticoagulation reversal agent.
Efloxate, a flavone derivative, could be effective in the treatment of chronic coronary insufficiency and angina pectoris for acting as a vasodilator.
Aceglutamide, also called as Glumal or acetylglutamine, is able to improve memory and concentration as psychostimulant and nootropic.
Ridogrel is a thromboxane synthase inhibitor used for the prevention of systemic thrombo-embolism. It is also a receptor antagonist that may be used as an adjun...