CCT251545 - CAS 1661839-45-7
Catalog number: 1661839-45-7
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C23H24ClN5O
Molecular Weight:
421.92
COA:
Inquire
Targets:
Wnt
Description:
CCT251545, a small molecule inhibitor of WNT signaling with oral activity, can be used as a selective chemical probe that exhibits >100-fold selectivity for the human Mediator complex–associated protein kinases CDK8 and CDK19 over 291 other kinases. IC50:
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Appearance:
Solid powder
Synonyms:
8-[3-chloro-5-[4-(1-methylpyrazol-4-yl)phenyl]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one CCT251545 CHEMBL3408213 8-(3-chloro-5-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one 8-{3-Chloro-5-[4-(1-Methyl-1h-Pyrazol-4-Yl)ph
Solubility:
DMSO: ≥ 50 mg/mL
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -64℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
Boiling Point:
709.7±60.0 °C | Condition: Press: 760 Torr
Density:
1.37±0.1 g/cm3
InChIKey:
LBFYQISQYCGDDW-UHFFFAOYSA-N
InChI:
1S/C23H24ClN5O/c1-28-15-18(12-27-28)16-2-4-17(5-3-16)19-13-25-14-20(24)21(19)29-10-7-23(8-11-29)6-9-26-22(23)30/h2-5,12-15H,6-11H2,1H3,(H,26,30)
Canonical SMILES:
CN1C=C(C=N1)C2=CC=C(C=C2)C3=CN=CC(=C3N4CCC5(CCNC5=O)CC4)Cl
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