|Targets||Checkpoint Kinase (Chk)|
|Description||CCT241533 (hydrochloride) is the hydrochloride salt form of CCT241533. As a potent Chk2 inhibitor, CCT241533 blocked CHK2 activity in human tumor cell lines in answer to DNA damage and potentiate PARP inhibitor cell killing. Chk2: IC50=3nM|
|Synonyms||(6E)-4-fluoro-6-[4-[[(3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3-yl]amino]-6,7-dimethoxy-1H-quinazolin-2-ylidene]cyclohexa-2,4-dien-1-one;hydrochloride C23H27FN4O4.ClH 1431697-96-9 3288AH 4-Fluoro-2-(4-(((3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3-yl)am|
|Solubility||Soluble in DMSO|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -44℃ for long term (months to years).|
|Shelf Life||2 years|
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