CCG 232601 - CAS 1922099-21-5
Category: Inhibitor
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Molecular Formula:
C24H20ClF2N3O2
Molecular Weight:
455.88
COA:
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Targets:
Others
Description:
CCG 232601 is a selective and orally bioactive inhibitor of the Rho/MRTF/SRF signaling pathway (IC50 value of 0.55 μM (SRE.L assay)) as a potential antifibrotic therapeutic for systemic scleroderma. CCG-232601 inhibits the development of bleomycin-induced dermal fibrosis in mice when administered orally.
Brife Description:
Rho/MRTF/SRF signaling pathway inhibitor
Purity:
99%
Synonyms:
N-(4-chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide; CCG-232601; CCG 232601; CCG232601.
MSDS:
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InChIKey:
MKJLDLGLVZUENS-UHFFFAOYSA-N
InChI:
InChI=1S/C24H20ClF2N3O2/c25-20-4-6-21(7-5-20)29-22(31)19-13-24(26,27)15-30(14-19)23(32)18-3-1-2-17(12-18)16-8-10-28-11-9-16/h1-12,19H,13-15H2,(H,29,31)
Canonical SMILES:
C1C(CN(CC1(F)F)C(=O)C2=CC=CC(=C2)C3=CC=NC=C3)C(=O)NC4=CC=C(C=C4)Cl
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CAS 1922099-21-5 CCG 232601

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