|Description||CCG 232601 is a selective and orally bioactive inhibitor of the Rho/MRTF/SRF signaling pathway (IC50 value of 0.55 μM (SRE.L assay)) as a potential antifibrotic therapeutic for systemic scleroderma. CCG-232601 inhibits the development of bleomycin-induced dermal fibrosis in mice when administered orally.|
|Brife Description||Rho/MRTF/SRF signaling pathway inhibitor|
|Synonyms||N-(4-chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide; CCG-232601; CCG 232601; CCG232601.|
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