CC122 - CAS 1015474-32-4
Catalog number: B0084-474963
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C14H14N4O3
Molecular Weight:
286.29
COA:
Inquire
Targets:
Others
Description:
CC122 is a novel agent for DLBCL. It is an orally available pleiotropic pathway modulator. It has antitumor and immunomodulatory activity. It is used for the treatment of chronic lymphocytic leukemia. It binds CRBN and degrades Aiolos and Ikaros resulting in a mimicry of IFN signaling and apoptosis in DLBCL. It inhibits proliferation and induces apoptosis in ABC and GCB DLBCL in vitro. It was developed by Celgene Corporation(CELG) and was in clinic phase 2 trial.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-474963 25 mg $298 In stock
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Purity:
>98 %
Related CAS:
1398053-45-6 (HCl salt)
Appearance:
Solid powder
Synonyms:
3-(5-Amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione;CC-122
Solubility:
DMSO ≥ 33 mg/mL
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
CC122 has antitumor and immunomodulatory activity. It is used for the treatment of chronic lymphocytic leukemia.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Grams to Kilograms
Density:
1.58±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
RSNPAKAFCAAMBH-UHFFFAOYSA-N
InChI:
InChI=1S/C14H14N4O3/c1-7-16-9-4-2-3-8(15)12(9)14(21)18(7)10-5-6-11(19)17-13(10)20/h2-4,10H,5-6,15H2,1H3,(H,17,19,20)
Canonical SMILES:
CC1=NC2=C(C(=CC=C2)N)C(=O)N1C3CCC(=O)NC3=O
Current Developer:
CC122 was developed by Celgene Corporation(CELG) and was in clinic phase 2 trial.
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CAS 1015474-32-4 CC122

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