CC-401 - CAS 862832-38-0
Catalog number:
862832-38-0
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
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Description:
CC-401 is A second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. Based on the chemistry of SP600125, another anthrapyrazolone inhibitor of JNK, CC-401 competitively binds the ATP binding site of JNK, resulting in inhibition of the phosphorylation of the N-terminal activation domain of transcription factor c-Jun; decreased transcription activity of c-Jun; and a variety of cellular effects including decreased cellular proliferation.
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Synonyms:
CC-401; CC 401; CC401.
MSDS:
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Current Developer:
Celgene Corporation
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CAS 862832-38-0 CC-401

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