CB5083 - CAS 1542705-92-9
Catalog number:
1542705-92-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C24H23N5O2
Molecular Weight:
413.4
COA:
Inquire
Targets:
p97
Description:
CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models . CB-5083 causes rapid and sustained accumulation of poly-ubiquitin in tumor xenografts after a single administration. CB-5083 showed activity to inhibit tumor growth in multiple rodent models of human cancer. Furthermore, CB-5083 appears to exhibit greater potency over current proteasome inhibitors that further validate targeting p97 and protein homeostasis in the treatment of cancer.
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Purity:
>98%
Appearance:
Solid powder
Synonyms:
CB5083; CB-5083; CB 5083.
MSDS:
Inquire
Quality Standard:
Enterprise Standard
Quantity:
Milligrams-Grams
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CAS 1542705-92-9 CB5083

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