|Description||A cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by the sarcolemmal Ca2+/Mg2+-ATPase. Its action is strongly potentiated by phospholipase A2.|
|Solubility||well in water and saline.|
|Storage||stable in freeze-dried state; in solution, keep at -20 °C.|
Synthetic, a weak AChR antagonist.
Seco-Duocarmycin GA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...
Sanguinarine is a toxic quaternary ammonium salt from the group of benzophenanthridine alkaloids. It is extracted from some plants, including bloodroot (Sanguin...
Diterpenoid alkaloids from the roots of Delphinium scabriflorum.
Diazoline is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.
Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
An inhibitor of MAO.
Brevetoxin PbTx 1
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
A hypolipidemic, antiatherosclerotic, anti-inflammatory agent, with angioprotective and hepatoprotective activity; antiulcerous. Sesquiterpene lactone , from pl...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.
Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker.
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Daunorubicin(RP13057) inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...
Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
Trichodesmine is a pyrrolizidine alkaloid that has neurotoxic effects and is naturally found in Crotolaria argyptiaca, a shrub plant that is native to the south...
GABA receptor antagonist