Cardiogenol c hydrochloride - CAS 1049741-55-0
Catalog number: 1049741-55-0
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Molecular Weight:
The hydrochloride salt form of Cardiogenol C, a pyrimidine derivative, might be able to induce embryonic stem cells (ESCs) into cardiomyocytes. It is significant in the cell-based therapy of heart disease. EC50: 100 nM.
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Related CAS:
1049741-55-0 (HCl); 671225-39-1 (Free base)
Solid powder
2-((2-((4-methoxyphenyl)amino)pyrimidin-4-yl)amino)ethan-1-ol hydrochloride; Cardiogenol C; Cardiogenol C HCl; Cardiogenol C hydrochloride
DMSO: > 59 mg/mL
-20ºC Freeze
The hydrochloride salt form of Cardiogenol C could be probably able to induce embryonic stem cells (ESCs) into cardiomyocytes.
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Canonical SMILES:
1.Cardiogenic shock associated with reversible dilated cardiomyopathy during therapy with regular doses of venlafaxine.
Charniot JC1, Vignat N, Monsuez JJ, Kidouche R, Avramova B, Artigou JY, Albertini JP. Am J Emerg Med. 2010 Feb;28(2):256.e1-5. doi: 10.1016/j.ajem.2009.05.010.
We report a cardiac complication in a patient treated with regular doses of venlafaxine. A 49-year-old man with prior normal cardiac function and stable chronic hepatitis C was treated for a major depressive disorder with usual doses of venlafaxine during an 8-month period until the occurrence of a cardiogenic shock in a context of dilated cardiomyopathy. Three months after withdrawal of the drug, the left ventricular ejection fraction returned to normal values. Cardiomyopathy is a rare complication with high doses of venlafaxine that was not previously reported in patients free of prior cardiac disease and cardiomyopathy and treated with usual doses (initially 150 mg daily; after 3 months, 75 mg daily). An objective assessment revealed that venlafaxine was probably implied in the subsequent development of cardiomyopathy when considering the Naranjo Probability Scale. Physicians who usually prescribe venlafaxine have to be briefed on such potential cardiac adverse effects even with usual doses.
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CAS 1049741-55-0 Cardiogenol c hydrochloride

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