|Description||Cardamonin is a naturally occuring chalcone initially isolated from the seeds of Amomum subulatum and subsequently from other zingiberous plant species. Cardamonin exhibits its antiinflammatory activity via suppression of p65NF-κB nuclear translocation and I-κBɑ phosphorylation.
is a novel antagonist ofhTRPA1cation channel with anIC50of 454 nM.
|Brife Description||A novel antagonist of hTRPA1 cation channel (IC50= 454 nM)|
|Synonyms||(E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one; 2',4'-dihydroxy-6'-methoxychalcone; cardamomin; cardamonin|
|Solubility||DMSO: ≥ 28 mg/mL|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||484.5±45.0 ℃ at 760 Torr|
|Melting Point||203-205 ℃|
Lipid peroxidation inhibitor 1
A lipid peroxidation inhibitor (IC50= 0.07 μM).
Ono-1082 increases cAMP levels in hepatocytes in rats.
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