Carbenicillin - CAS 4697-36-3
Catalog number:
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Molecular Weight:
Carbenicillin is broad-spectrum semisynthetic penicillin derivative used parenterally. It is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.
Publictions citing BOC Sciences Products
  • >> More
1.Utility of surface enhanced Raman spectroscopy (SERS) for elucidation and simultaneous determination of some penicillins and penicilloic acid using hydroxylamine silver nanoparticles.
El-Zahry MR1, Refaat IH2, Mohamed HA2, Rosenberg E3, Lendl B3. Talanta. 2015 Nov 1;144:710-6. doi: 10.1016/j.talanta.2015.07.015. Epub 2015 Jul 10.
Elucidation and quantitative determination of some of commonly used penicillins (ampicillin, penicillin G and carbenicillin) in the presence of their main degradation product (penicilloic acid) were developed. Forced acidic and basic degradation processes were applied at different time intervals. The formed degradation products were elucidated and quantified using surface enhanced Raman spectroscopy (SERS). Silver nanoparticles (AgNPs) prepared by reduction of silver nitrate using hydroxylamine-HCl in alkaline medium were used as SERS substrate. The results obtained in SERS were confirmed by the application of LC/MS method. The concentration range was 100-600 ng/ml in case of the studied penicillins and 100-700 ng/ml in case of penicilloic acid. An excellent correlation coefficient was found in case of ampicillin (r=0.9993) and in the case of penicilloic acid (r=0.9997). Validation procedures were carried out including precision, robustness and accuracy by comparing F- and t-values of both the proposed and reported methods.
2.Detection and Characterization of Antimicrobial Resistance and Putative Virulence Genes in Aeromonas veronii Biovar Sobria Isolated from Gilthead Sea Bream (Sparus aurata L.).
Gashgari RM1, Selim SA2,3. Foodborne Pathog Dis. 2015 Sep;12(9):806-11. doi: 10.1089/fpd.2015.1976. Epub 2015 Jul 28.
The purposes of this study were to investigate the antimicrobial resistance of Aeromonas veronii biovar sobria isolated from gilthead sea bream and to characterize the virulence-implicated genes. Fish samples (n=365) were collected from wholesale and retail markets in Aljouf, Saudi Arabia between 2013 and 2014. A total of 45 A. veronii biovar sobria isolates (12.3%) from those samples were tested for resistance to a range of antimicrobial agents. All strains exhibited 100% resistances to nalidixic acid, carbenicillin, cephalothin, erythromycin, kanamycin, tetracycline, and trimethoprim-sulfamethoxazole. Additionally, the highest susceptibility encountered was to ciprofloxacin (100%). In the present study, we examined the presence of several genes, including aerolysin, elastase, lipase, flagellin, enterotoxin, and DNases, that code for putative virulence factors that may play important roles in bacterial infection. It was found that all of these genes were common in these strains.
3.Purification and characterization of a new β-lactamase OXA-205 from Pseudomonas aeruginosa.
Krasauskas R1, Labeikytė D2, Markuckas A3, Povilonis J4,5, Armalytė J6, Plančiūnienė R7, Kavaliauskas P8, Sužiedėlienė E9. Ann Clin Microbiol Antimicrob. 2015 Nov 26;14:52. doi: 10.1186/s12941-015-0113-1.
BACKGROUND: We have identified a novel class 1 integron (1503 bp), named In671 in a clinical Pseudomonas aeruginosa isolate. Integron sequence analysis revealed two gene cassettes, one coding for a new OXA-type β-lactamase designated as OXA-205 and the other coding for the aadB gene that is responsible for aminoglycoside resistance. The 266 amino acid sequence of OXA-205 revealed that this β-lactamase belongs to the Ambler class D showing highest sequence homology to the OXA-2 sub-lineage. Our objective was to purify and characterize β-lactamase OXA-205.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Antibacterial Products

CAS 179033-51-3 Timcodar

(CAS: 179033-51-3)

Timcodar, a pyridine derivative, has been found to be a p-glycoprotein inhibitor as well as nerve growth factor stimulant and was once studied in the treatment ...

CAS 217500-96-4 Tulathromycin A

Tulathromycin A
(CAS: 217500-96-4)

Triamilide antibiotic for treatment of bovine and porcine respiratory disease. Exists as an equilibrium mixture of two isomeric forms, Tulathromycin A (90%) and...

CAS 186826-86-8 Moxifloxacin HCl

Moxifloxacin HCl
(CAS: 186826-86-8)

Moxifloxacin exerts its effects by trapping a DNA drug enzyme complex and specifically inhibiting ATP-dependent enzymes topoisomerase II (DNA gyrase) and topoisom...

CAS 79-57-2 Oxytetracycline

(CAS: 79-57-2)

Oxytetracycline (Terramycin) was the second of the broad-spectrum tetracycline group of antibiotics to be discovered.

CAS 80621-81-4 Rifaximin

(CAS: 80621-81-4)

Rifaximin, an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity.

CAS 80-08-0 Dapsone

(CAS: 80-08-0)

Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and i...

CAS 13009-99-9 Mafenide Acetate

Mafenide Acetate
(CAS: 13009-99-9)

Mafenide is a bacteriostatic antibiotic with a broad activity against Gram positive, Gram negative bacteria and Clostridia. Mafenide acetate penetrates eschar a...

CAS 131-69-1 Phthalylsulfacetamide

(CAS: 131-69-1)

Phthalylsulfacetamide, a sulfanilamide derivative, is a predrug of sulfacetamide and could be used as an antibacterial agent.

CAS 219552-69-9 Parasin I

Parasin I
(CAS: 219552-69-9)

Parasin I, a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, is a cell permeable cationic antimicrobial agent.

CAS 1070-11-7 Ethambutol HCl

Ethambutol HCl
(CAS: 1070-11-7)

Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

CAS 78964-85-9 Fosfomycin Tromethaminel

Fosfomycin Tromethaminel
(CAS: 78964-85-9)

Fosfomycin is a broad-spectrum antibiotic. It was produced by certain Streptomyces species. But now it can be made by chemical synthesis

(CAS: 1174018-99-5)

Relebactam, a diazabicyclooctane derivatice, has wide spectrum inhibiting activity of β-lactamases. It has been stuied to be probably effective in the treatment...

CAS 62893-19-0 Cefoperazone

(CAS: 62893-19-0)

Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.

CAS 80214-83-1 Roxithromycin

(CAS: 80214-83-1)

Roxithromycin is a semi-synthetic macrolide antibiotic that inhibits bacterial cell growth and replication. It is used to treat respiratory tract, urinary and s...

CAS 6054-98-4 Olsalazine Sodium

Olsalazine Sodium
(CAS: 6054-98-4)

Olsalazine Sodium is an anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond. It is used in the treatment of inflammatory bowel...

CAS 651-06-9 Sulfameter

(CAS: 651-06-9)

Sulfameter is a long-acting sulfonamide antibacterial. It is used as a leprostatic agent and in the treatment of urinary tract infections.

CAS 37321-09-8 Apramycin

(CAS: 37321-09-8)

Apramycin stands out among aminoglycosides for its mechanism of action which is based on blocking translocation and its ability to bind also to the eukaryotic d...

CAS 123447-62-1 Prulifloxacin

(CAS: 123447-62-1)

Prulifloxacin prevents bacterial DNA replication, transcription, repair and recombination through inhibition of bacterial DNA gyrase.

CAS 140896-21-5 Indolicidin

(CAS: 140896-21-5)

Indolicidin is the smallest of the naturally known occurring linear antimicrobial peptides, containing the highest percentage of tryptophan of any known protein...

CAS 65710-07-8 Apramycin Sulfate

Apramycin Sulfate
(CAS: 65710-07-8)

Apramycin is an aminoglycoside antibiotic. It acts by blocking translocation and binding also to the eukaryotic decoding site despite differences in key residue...

Chemical Structure

CAS 4697-36-3 Carbenicillin

Quick Inquiry

Verification code

Featured Items