|Description||Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.|
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Delsoline is a hypotensive alkaloid isolated from Aconitum.
Synthetic, a neuronal nicotinic AChR antagonist.
An inhibitor of MAO.
Daun02 is a daunorubicin b-galactoside prodrug for use in conjunction.
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab ma...
Xanthonoid Purified from Hypericum perforatum
Seco-Duocarmycin MA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
It was the main alkaloid found in medicinal plants Datura metel. .
20-Hydroxyecdysone (ecdysterone or 20E) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods. It i...
DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Quinoline alkaloid , from plants of the Rutaceae family, an anticonvulsant; causes hypothermia; inhibits the reaction of orientation; prevents cardiac arrhythmi...
An excitatory scorpion toxin. Polypeptide, of 77 amino acids cross-linked by 4 disulfide bridges. Recombinant toxin produced in<br/>Escherichia coli initialy fr...
Hydrobromide salt of (+)-Lappaconitine, a potential antitumor agent agent that induces HL-60 differentiation and apoptosis with analgesic activity as well.
Alkaloid from reticuline and is a precursor of berberine.It has also been found to be a GABAA receptor agonist.
A Na+ channel blocker; potent antiarrhythmic, inhibits voltage-gated Na+ channels in rat brain synaptosomes.
Condelphine was isolated from the roots of Delphinium denudatum. A nicotinic receptor antagonist at the neuromuscular junction and ganglioblocking agent.
A cytostatic substance Isotryptamine.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Diazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular rel...