Calcium N5-methyltetrahydrofolate - CAS 26560-38-3
Catalog number:
26560-38-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H23CaN7O6
Molecular Weight:
497.52
COA:
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Targets:
Antifolate
Description:
A metabolite of Folic acid; inhibits photosensitization reactions and strand breaks in DNA; reduces total serum homocysteine level in orthotopic liver transplant recipients.
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Purity:
>98%
Synonyms:
NSC173328
MSDS:
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1.Antioxidant activity comparison between [6S]-5-methyltetrahydrofolic acid calcium salt and the related racemate form.
Merola N1, Alonso FJ, Ros G, Castón MJ. Food Chem. 2013 Jan 15;136(2):984-8. doi: 10.1016/j.foodchem.2012.09.020. Epub 2012 Sep 19.
Folates, such as [6S]-5-methyltetrahydrofolic acid, have been introduced in the market both in vitamin pills and in fortified foods. Their antioxidant activity has been evaluated, but stereoisomer influence on activity has not been proven. In this study, a comparison between [6S]-5-methyltetrahydrofolic acid (5-MTHF) and its racemate [6R,S] form was made by TEAC assay at different pHs, FRAP assay, and ORAC assay. The results showed that the [6S] form had higher antioxidant activity than its racemate form in the TEAC assay at all pHs, with similar values in the FRAP and ORAC assays. Results suggest that stereoisomeric difference could influence the antioxidant activity of 5-MTHF and hence should be taken into account when folates are added to foodstuffs to improve their nutritional value.
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CAS 26560-38-3 Calcium N5-methyltetrahydrofolate

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