|Description||A potent calcium ionophore isolated from streptomyces chartreusis in 1974; a spiroketal substituted by pyrollic and benzoxazolyl groups which afford its high affinity and selectivity for calcium; exhibits broad biological activity against bacteria, fungi and protozoa; a research tool for calcium-regulated cellular events.|
|Purity||>99% by HPLC|
|Synonyms||A 23187, Calimycin|
|Solubility||Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.|
An unusual pyrollic ionophore active against gram positive bacteria and insects; has antihypertensive properties; a growth promoter in ruminants.
The major analogue of the concanamycin complex produced by streptomyces sp.; a potent and specific vacuolar-atpase inhibitor; inhibits the acidification of orga...
Actinomycin D is a polypeptide antibiotic isolated from soil bacteria of the genus Streptomyces. It binds to double-stranded DNA and forms a complex, resulting ...
An unusual indolocarbazole alkaloid produced by a range of actinomycete species; a potent antitumour active, inducing apoptosis in a variety of cell lines; a po...
A tetrahydroxyanthrone; active against bacteria, including mycobacteria, and viruses; induces apoptosis and inhibits RNA polymerase.
A minor analogue of the herbimycin complex; isolated from streptomyces hygroscopicus; exhibits antitumour activity
Geldanamycin is a benzoquinone ansamycin antibiotic isolated from streptomyces hygroscopicus. It acts as a potent antitumour agent by binding to the 90-kda heat...
One of two components found in the glycopeptide antibiotic bleomycin sulfate; a chemotherapeutic agent used for the treatment of hodgkins lymphoma