|Description||Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities.|
|Synonyms||CAPE; Caffeic Acid Phenethyl Ester; BAF-IN-C09; 2-Phenylethyl Caffeate; β-Phenylethyl Caffeate;|
BQU57, a derivative of RBC8, is a selective GTPase Ral inhibitor relative to the GTPases Ras and RhoA.
GSK2578215A induces a dose-dependent inhibition of Ser910 and Ser935 phosphorylation in both wild-type LRRK2 and LRRK2[G2019S] stably transfected into HEK293 ce...
Pifithrin-μ (PFT-μ) is an inhibitor of p53-mediated apoptosis, preventing p53 binding to Bcl-xL (Kd = 0.82 mM) and Bcl-2 (Kd = 0.80 mM) at the mitochondria with...
ONO-1301, a naphthalen derivative, has been found to be a prostacyclin agonist and could be studied as an anti-inflammatory agent works partially through leadin...
The hydrochloride salt form of SAR7334, a TRPC6 inhibitor, could be valuable in studying sorts of diseases related to TRPC.
Amfenac sodium monohydrate
Amfenac is a COX inhibitor with IC50 of 0.25 and 0.15 μM for COX-1 and COX-2, respectively.
β-[[[4,5-Dihydro-5-[2-(1H-imidazol-2-ylamino)ethyl]-3-isoxazolyl]carbonyl]amino]-3,4-dihydro-γ-oxo-2(1H)-Isoquinolinebutanoic Acid is a de...
Vidofludimus is an orally active and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 134 nM for human DHODH. Phase 2.