Cabraleahydroxylactone - CAS 35833-69-3
Catalog number: 35833-69-3
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Molecular Weight:
Chemical Family:
Cabraleahydroxylactone isolated from the herbs of Aglaia lawii.
(5S)-5-[(3α,5α,17β)-3-Hydroxy-4,4,8,10,14-pentamethylgonan-17-yl] -5-methyldihydro-2(3H)-furanone; 3-hydroxy-25,26,27-trinordammaran-24,20-olide;
antiviral activity
Quality Standard:
Enterprise Standard
1.Activity-guided isolation of cytotoxic constituents from the bark of Aglaia crassinervia collected in Indonesia.
Su BN;Chai H;Mi Q;Riswan S;Kardono LB;Afriastini JJ;Santarsiero BD;Mesecar AD;Farnsworth NR;Cordell GA;Swanson SM;Kinghorn AD Bioorg Med Chem. 2006 Feb 15;14(4):960-72. Epub 2005 Oct 10.
Activity-guided fractionation of a CHCl(3)-soluble partition of the MeOH extract of the bark of Aglaia crassinervia collected in Indonesia led to the isolation of three new glabretal-type triterpenoids, aglaiaglabretols A-C (1-3), as well as nine known compounds, 3-epi-cabraleahydroxylactone (4), cabraleahydroxylactone (5), rocaglaol (6), 2beta,3beta-dihydroxy-5alpha-pregn-17(20)-(E)-16-one, scopoletin, and mixtures of cabraleadiol and epicotillol and of beta-sitosterol and stigmasterol. The structures of compounds 1-3 were determined on the basis of spectroscopic and chemical methods. The structure of aglaiaglabretol A (1) was confirmed by single-crystal X-ray analysis, and the absolute stereochemistry of this isolate was established by the Mosher ester method. The cytotoxic activity of all isolates and several chemical transformation products obtained in the present study was evaluated. The known cyclopenta[b]benzofuran, rocaglaol (6), was found to be significantly active and comparable in potency to the positive controls, paclitaxel and camptothecin. Aglaiaglabretol B (2) was further tested in an in vivo hollow fiber model.
2.A new sesquiterpene and other terpenoid constituents of Chisocheton penduliflorus.
Phongmaykin J;Kumamoto T;Ishikawa T;Suttisri R;Saifah E Arch Pharm Res. 2008 Jan;31(1):21-7.
A new aromadendrane sesquiterpene, allo-aromadendrane-10alpha, 14-diol (3), was isolated from Chisocheton penduliflorus (Meliaceae), along with two known sesquiterpenes: allo-aromadendrane-10beta, 14-diol (2) and allo-aromadendrane-10beta, 13, 14-triol (7). Six dammarane triterpenoids, including cabraleadiol (1), eichlerialactone (4), cabraleahydroxylactone (5), cabralealactone (6), hollongdione (8) and dammaradienone (9), the coumarins scoparone and scopoletin, and vanillic acid were also isolated from the wood and leaves of this plant. Compounds 1-7 displayed antimycobacterial activity against Mycobacterium tuberculosis. Compounds 1, 4, 5 and 6 were weakly cytotoxic to a breast cancer (BC) cell line; whereas, compound 6 was moderately active against a small-cell lung cancer (NCI-H187) cell line.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Triterpenoids Products

CAS 155683-00-4 Notoginsenoside Ft1

Notoginsenoside Ft1
(CAS: 155683-00-4)

Notoginsenoside Ft1, a new saponin solated from the leaves of P. notoginseng, as a stimulator of angiogenesis it is more potent compared with other bioactive sa...

CAS 260393-05-3 Zamanic acid

Zamanic acid
(CAS: 260393-05-3)

Zamanic acid is a natural plant triterpenoid isolated from the herbs of Plumeria obtusa.

CAS 63543-53-3 24,25-Dihydroxydammar-20-en-3-one

(CAS: 63543-53-3)

24,25-Dihydroxydammar-20-en-3-one isolated from the herbs of Walsura robusta.

CAS 6610-56-6 Glochidiol

(CAS: 6610-56-6)

Glochidiol isolated from the herbs of Glochidion puberum L.

Pulchinenoside E3
(CAS: 824401-07-2)

Pulchinenoside E3 is a triterpenoids pulchinenoside standard extracted from Pulsatilla. Pulchinenoside has effects on chickens immune.

CAS 6199-67-3 cucurbitacin B

cucurbitacin B
(CAS: 6199-67-3)

Cucurbitacin B, which can be extracted from the rhizomes of Hemsleya amabilis Diels, has profound in vitro and in vivo antiproliferative effects against human p...

CAS 149252-87-9 1-Dehydroxy-23-deoxojessic acid

1-Dehydroxy-23-deoxojessic acid
(CAS: 149252-87-9)

1-Dehydroxy-23-deoxojessic acid is isolated from the herbs of Gardenia sootepensis

CAS 181225-33-2 Ginsenoside F4

Ginsenoside F4
(CAS: 181225-33-2)

Ginsenoside F4 is extracted from the root of Panax ginseng C. A. Mey. It has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis. It was f...

CAS 2023822-39-9 Scillascillol

(CAS: 2023822-39-9)

Scillascillol is a natural compound isolated from the whole plants of Scilla scilloides.

CAS 252351-95-4 Lucidadiol

(CAS: 252351-95-4)

Lucidadiol is a natural compound isolated from the fruitbody of Ganoderma pfeifferi.

CAS 80418-24-2 Notoginsenoside R1

Notoginsenoside R1
(CAS: 80418-24-2)

Notoginsenoside R1 is a natural triterpenoid compound found in the roots of Panax notoginseng (Burk.)F.H.Chen. Notoginsenoside R1 exhibits antioxidant and antia...

(CAS: 19891-85-1)

29-Nor-20-oxolupeol is a natural triterpenoid compound found in several plants.

CAS 39903-21-4 29-Hydroxyfriedelan-3-one

(CAS: 39903-21-4)

29-Hydroxyfriedelan-3-one isolated from the herbs of Euonymus alatus (Thunb.) Sieb.

CAS 35833-70-6 Cabraleahydroxylactone acetate

Cabraleahydroxylactone acetate
(CAS: 35833-70-6)

Cabraleahydroxylactone acetate isolated from the herbs of Aglaia lawii.

CAS 80489-65-2 Rubifolic acid

Rubifolic acid
(CAS: 80489-65-2)

Rubifolic acid is a natural compound isolated from the herbs of Galium verum.

CAS 508-04-3 13(18)-Oleanen-3-ol

(CAS: 508-04-3)

13(18)-Oleanen-3-ol isolated from the herbs of Cucurbita pepo L.

CAS 283174-18-5 11β-Hydroxycedrelone

(CAS: 283174-18-5)

11β-Hydroxycedrelone, a natural triterpenoid isolated from the barks of Walsura yunnanensis, has the activities of cytotoxic and anti-inflammatory.

CAS 152253-67-3 Mupinensisone

(CAS: 152253-67-3)

Mupinensisone is a natural triterpenoid found in the herbs of Celastrus paniculatus.

CAS 62025-50-7 Ginsenoside F3

Ginsenoside F3
(CAS: 62025-50-7)

Ginsenoside F3 is extracted from the root of Panax ginseng C. A. Mey. It has immunoenhancing activity by regulating production and gene expression of type 1 cyt...

Chemical Structure

CAS 35833-69-3 Cabraleahydroxylactone

Quick Inquiry

Verification code

Featured Items