|Description||trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a well-known fatty acid synthase (FAS) inhibitor. Studies show that trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a cell cycle arrest inducer in hepatocellular carcinoma (HCC) cell lines. It has also been shown to blocks resistin-induced increases in lipid accumulation by human macrophages.|
|Synonyms||C 75 trC-75 trans-racemic; trans-C75|
20-O-Acetylingenol-3-angelate is a natural compound extracted from Euphorbia conspicua N. E. Br. It is used as molluscicidal agent, anti-cancer agent and cytost...
Cinobufagin can inhibit the proliferation of U-2OS cells, and induce cell apoptosis. The potential mechanism of Cinobufagin-induced apoptosis may be related to ...
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, ...
Ponatinib hydrochloride is an oral drug for the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome–positive (Ph+) acute lymphoblastic leuke...
Probenecid is an inhibitor of organic-anion transporters located in cell membranes, and it is used as a medication for the treatment of gout and hyperuricemia.
NSC134754 is a Heat Shock Factor 1 (HSF1) inhibitor. It can induce inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating lig...
AM-TS23 has been found to be a DNA polymerase λ and β inhibitor and could be effective in studies of colorectal cancer.
DIM-C-pPhOH is a Nur77 (NR4A1) antagonist. It inhibits TGF-β induced cell migration in breast cancer cell lines, and promotes ROS/endoplasmic reticulum stress a...