|Description||C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS), which is used as a tool for studying fatty acid synthesis in metabolic disorders and cancer.|
|Synonyms||C 75 trC-75 trans-racemic; trans-C75|
Polycomb complex protein BMI-1 is a polycomb ring finger oncogene that regulates the p16 and p19 cell cycle inhibitor genes. It is necessary for efficient self-...
Butylhydroxyanisole, also called as AMIF 72, Nipantiox 1 F or Butyl Methoxyphenol, with antioxidative property it is used as a food additive preservative.
MK 410 is an anti-inflammatory drug which can induce alterations in the immune system by the suppression of plasma neutral proteinase activity.
BVT 2733 is a non-steroidal small molecule as a a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC = 96 ± 14 nM w).
Mulberroside A, extracted from the root bark of white mulberry, could reduce P-gp expression and function being along with the activation of PKC and NF-κB. It h...
GS 389 is a novel tetrahydroisoquinoline analog which significantly increased cGMP levels in the rat aorta and inhibited cGMP phosphodiesterase from the rabbit ...
Dimesna is a synthetic derivative of dithio-ethane sulfonate with uroprotective properties. In the kidney, dimesna undergoes reduction to the free thiol compoun...
TPY-5628, a pyrrole derivative, has been found to be commonly used in sorts of chemical areas like anticancer drugs as an significant intermediate.
HSR60716071, a novel pyrazinecarboxamide derivative, exhibits potent inhibition of the IgE-mediated passive cutaneous anaphylaxis (PCA) in rats on oral administ...
Potent and competitive kynurenine 3-hydroxylase inhibitor (IC50 = 37 nM). Shows antidystonic, anticonvulsant and neuroprotective effects in vivo. Blood-brain ba...
Sodium lauryl polyoxyethylene ether sulf
Sodium lauryl polyoxyethylene ether sulfate is an anionic detergent and surfactant found in many personal care products, such as soaps, shampoos, toothpaste etc...
Astragaloside I is a saponin found in the root of Astragalus membranaceus (Fisch.) Bunge, which is known as huáng qí in Traditional Chinese Medicine. It has car...
Palmatine hydrochloride (Palmatine chloride (6CI,7CI)) is a hydrochloride salt of palmatine which is a protoberberine alkaloid, has been used in the treatment o...
Hexafluronium bromide is .a cholinesterase inhibitor used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium durin...
MDL-72274 is a selective SSAO inhibitor. It is a potent (IC50 = 10(-9) M) inhibitor of both MAO-B and SSAO, with 190-fold lower affinity for MAO-A. MDL-72974 ca...
Genistinis, a derivative of Genistein, is selective inhibitor of mammalian terminal deoxynucleotidyl transferase.
Isolated from the seed of Coix lacryma-jobi L. var. meyuan (Romen.) Stapf acts as a central muscle relaxant with an anti-convulsant effect.
Arbutin is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos. It inhibits tyrosinase and thus prevents the...
SYR127063 is a selective HER2 inhibitor with IC50 value of 11 nM for HER2, and > 10000 nM for HER4. It can bind to HER2 in an active-like conformation.