C16 - CAS 608512-97-6
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C13H8N4OS
Molecular Weight:
268.29
COA:
Inquire
Targets:
Others
Description:
C16 is an inhibitor of RNA-activated protein kinase (PKR) (IC50 = 210 nM). It is an imidazolo-oxindole derivative that binds to ATP-binding site of PKR and rescues PKR-dependent translation block in vitro. C16 has neuroprotective activity against cell damage in human neuroblastoma cells and neuroinflammation in acute excitotoxic rat model.
Brife Description:
PKR inhibitor
Purity:
≥98% by HPLC
Appearance:
Orange Solid
Synonyms:
GW-506033X; GW 506033X; GW506033X; C16, PKR Inhibitor; 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one
MSDS:
Inquire
Melting Point:
>225°C (dec.)
InChIKey:
VFBGXTUGODTSPK-BAQGIRSFSA-N
InChI:
InChI=1S/C13H8N4OS/c18-13-8(3-7-4-14-5-15-7)11-9(17-13)1-2-10-12(11)19-6-16-10/h1-6H,(H,14,15)(H,17,18)/b8-3-
Canonical SMILES:
C1=CC2=C(C3=C1NC(=O)C3=CC4=CN=CN4)SC=N2
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


PD-116779
(CAS: 102674-89-5)

PD-116779 is a novle antitumor antibiotic belonging the benz[a]anthraquinone class.

CAS 61281-38-7 Schisandrin A

Schisandrin A
(CAS: 61281-38-7)

Schizandrin A is extracted from the seeds of Schisandra chinensis (Turcz.) Baill that is reported to have liver-protective, antitumor, and antioxidant activitie...

CAS 36338-96-2 Safflower Yellow

Safflower Yellow
(CAS: 36338-96-2)

Extract from Carthamin, widely used for the treatment of acute ischemic stroke by acting directly on BV2 microglia.

Azoramide
(CAS: 932986-18-0)

Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It is a dual-function endoplasmic reticulum (ER) modulator in vitro. It im...

CAS 1213-06-5 Etebenecid

Etebenecid
(CAS: 1213-06-5)

Etebenecid, a benzenesulfonic acid derivative, could be used to reduce uric acid levels acting as a uricosuric agent.

CAS 114084-78-5 Ibandronic acid

Ibandronic acid
(CAS: 114084-78-5)

Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.

CAS 1582-09-8 Trifluralin

Trifluralin
(CAS: 1582-09-8)

Trifluralinis a pre-emergence herbicide, because it causes absence of microtubule which leads to prevents the completion of plant cell division. However, it doe...

CAS 490-46-0 (-)-Epicatechin

(-)-Epicatechin
(CAS: 490-46-0)

(−)-Epicatechin is a 2R,3R stereoisomer of catechin and is a naturally occurring flavanol. It is a powerful antioxidant and could inhibit cyclooxygenase.

Chemical Structure

CAS 608512-97-6 C16

Quick Inquiry

Verification code

Featured Items