|Molecular Formula||C20H24N10O12P2 (free acid)|
|Molecular Weight||658.4 (free acid)|
|Description||c-diAMP was recognized as a second messenger for signalling DNA integrity in Bacillus subtilisduring sporulation, and an additional purine-based signalling nucleotide with a more general function in prokaryotes.|
|Purity||≥ 98% by HPLC (typically ≥ 99%)|
|Synonyms||Cyclic diadenosine monophosphate, sodium salt|
8-Cl-cAMP-AM is a precursor of 8-Cl-cAMP, the PKA activator. The polar active analogue is released after the metabolism of 8-Cl-cAMP-AM by esterases.
2'-O-Me-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which is used to study ligand-receptor interactions.
8-AET-cGMP-Agarose is the second messenger cGMP immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucle...
8-MA-cAMP is a selective cAMP analogue that has affinity to site B of protein kinase A type I and II. Site A activity is developed when 8-MA-cAMP acts synergist...
Sp-8-Br-2'-O-Me-cAMPS is a anti-hydrolytic form of 8-Br-2'-O-Me-cAMP, a specific membrane-permeant stimulator of the exchange protein activated by cAMP (Epac) o...
Sp-2-AEA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatogra...
2'-AHC-cCMP is an analogue of cCMP used as a ligand in affinity chromatography of cCMP binding proteins or for coupling of labelling structures such as fluoroph...
Sp-6-AH-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and oth...
c-(ApGp) / 3'3'-cGAMP
c-(ApGp) is an analogue of c-diAMP and c-diGMP, the bacterial second messengers, which plays a role in Vibrio choleraepathogenesis and activates the production ...
ara-cAMP is an analogue of cAMP, the second messenger. It is commonly used in receptor mapping studies and negative controls.
EtOH-NH-Agarose is the agarose gel without nucleotide immobilized on it, which can be used as negative control in affinity chromatography experiments.
2-AH-cGMP is a ligand in affinity chromatography of cGMP binding proteins and can be modified with fluorophores.
8-Br-cGMP-AM is a precursor of 8-Br-cGMP, the PKG activator. The polar active analogue is released after the metabolism of 8-Br-cGMP-AM by esterases.
2'-NH2-cAMP is often used in affinity chromatography of cAMP and cGMP binding proteins for its amino group used as a ligand, which do not require an intact 2'-O...
8-pCPT-2'-O-Me-cAMP is a PDE-stable activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It has hig...
6-AH-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminohexyl spacer which can be used in affinity chromatography of cyclic nucleotide-...
2-ADOA-cAMP is a hydrophilic analogue of cAMP, which is used as a ligand in affinity chromatography and can be modified with fluorophores.