|Molecular Formula||C20H23BrN10O13P2 (free acid)|
|Molecular Weight||753.3 (free acid)|
|Description||c-(Ap-8-Br-Gp) is an analogue of c-(ApGp), the potential bacterial second messenger, which is used for binding studies and as precursor for further modifications with spacers or labels. c-(ApGp) plays a role in Vibrio choleraepathogenesis and activates the production of interferon via STING.|
|Purity||≥ 95% by HPLC|
|Synonyms||Cyclic (adenosine monophosphate- 8- bromoguanosine monophosphate), sodium salt|
2'-O-MS-TME-cGMP is an analogue of cGMP, which is used for radio-iodination in cGMP immunoassays.
8-AET-2'-O-Me-cAMP is a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activ...
2',2''-Di-O-Me-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which selectively binds the c-diGMP class II riboswitch. It can be used to dis...
ara-cAMP is an analogue of cAMP, the second messenger. It is commonly used in receptor mapping studies and negative controls.
c-(Ap-8-Biotin-11-Gp) is an analogue of the cyclic dinucleotide c-(ApGp). It is a potential tracer in immunoassays and commonly used for affinity chromatography...
2'-AEC-cAMP-Agarose is the protein kinase A activator cAMP immobilized on agarose by an aminoethylcarbamoyl spacer, wihch can be used in affinity chromatography...
Sp-2'-AHC-cAMPS is a PDE-stable analogue of cAMP used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores.
8-Br-cAMP-AM is a precursor of the PKA activator 8-Br-cAMP. The polar active analogue is released after metabolism of 8-Br-cAMP-AM by esterases.
8-pCPT-2'-O-Me-cAMP is a PDE-stable activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It has hig...
2'-AHC-cCMP-Agarose is the putative second messenger cCMP immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chromatography ...
8-Br-2'-O-Me-cGMP is an analogue of cGMP that does not activate both protein kinase G and Epac. It is often used as an inactive control versus 8-Br-cGMP.
2',2''-Di-AHC-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of la...
Sp-8-Cl-cAMPS is a resistant stimulator of protein kinase A, the cAMP agonist. Compared with 8-Cl-cAMP, it has the increased lipophilic and membrane-permeant pr...
1-NH2-cGMP is a selective cGMP analogue that has a higher affinity of site A in cGK, and it is commonly used for synergism studies.
8-APT-cGMP is an isozyme-selective stimulator of cGMP-dependent protein kinase I a with a prenference for type I a over I by a factor of 200.