|Molecular Formula||C20H23BrN10O13P2 (free acid)|
|Molecular Weight||753.3 (free acid)|
|Description||c-(Ap-8-Br-Gp) is an analogue of c-(ApGp), the potential bacterial second messenger, which is used for binding studies and as precursor for further modifications with spacers or labels. c-(ApGp) plays a role in Vibrio choleraepathogenesis and activates the production of interferon via STING.|
|Purity||≥ 95% by HPLC|
|Synonyms||Cyclic (adenosine monophosphate- 8- bromoguanosine monophosphate), sodium salt|
1-NH2-cGMP is a selective cGMP analogue that has a higher affinity of site A in cGK, and it is commonly used for synergism studies.
Sp-8-Br-cGMPS is an activator of protein kinase G I α and protein kinase A. It has a resistant effect against cyclic nucleotide phosphodiesterases. Compared to ...
Sp-8-Br-2'-O-Me-cAMPS is a anti-hydrolytic form of 8-Br-2'-O-Me-cAMP, a specific membrane-permeant stimulator of the exchange protein activated by cAMP (Epac) o...
c[8-Biotin-11-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger. It is a potential tracer in immuno...
2-Cl-ATP is an agonist of P2Y purinoceptor that inhibits soluble guanylate cyclase.
cGMP-AM is a precursor of cGMP, the second messenger. The polar active analogue is released after the metabolism of cGMP-AM by esterases.
Sp-2-AHA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatogra...
c-diAMP was recognized as a second messenger for signalling DNA integrity in Bacillus subtilisduring sporulation, and an additional purine-based signalling nucl...
Sp-2'-AEC-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and o...
8-AET-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucle...
6-AE-cAMP-Agarose is the second messenger cAMP immobilized on agarose by an aminoethyl spacer which can be used in affinity chromatography of cyclic nucleotide-...
Sp-c-diAMPS is an analogue of c-diAMP, the bacterial second messenger.
Rp,Rp-c-diGMPSS is an analogue of c-diGMP, the bacterial second messenger, with improved stability. It can be used to study ligand-receptor interactions.
8-AEA-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It can be modified with fluorophores and other markers.
Sp-cGMPS is a resistant stimulator of cGMP-dependent protein kinases.
c-(Ap-8-AET-Gp)-Agarose is the bacterial second messenger c-(ApGp) immobilized on agarose by an aminoethylthio spacer, which possibly can be used in affinity ch...
2'-O-MS-cAMP is a cAMP analogue used for coupling of ligands including proteins for ELISA.
Rp-8-AET-cGMPS-Agarose is the metabolically stable protein kinase G inhibitor Rp-cGMPS immobilized on agarose by an aminoethylthio spacer, which can be used in ...
Rp-2'-AEC-cAMPS-Agarose is the protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chroma...
Rp-8-AHA-cAMPS is a PDE-resistant analogue of Rp-cAMPS, the PKA inhibitor, which is used for immobilization as an affinity ligand or for coupling of labelling s...