|Molecular Formula||C27H38N12O14P2 (free acid)|
|Molecular Weight||816.6 (free acid)|
|Description||c[3'-AHC-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which can be used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores.|
|Purity||≥ 95% by HPLC|
|Synonyms||Cyclic (3'- O- (6- aminohexylcarbamoyl)guanosine- (2' −≥ 5')- monophosphate- adenosine- (3' −≥ 5')- monophosphate), sodium salt|
cAMP-AM is a membrane-permeant precursor of cAMP, the second messenger. cAMP is released after permeation and metabolism of cAMP-AM by esterases, then it is met...
Rp-8-AET-cGMPS is a ligand in affinity chromatography and can be modified with fluorophores or other markers.
2-AHA-cAMP is a ligand in affinity chromatography and can be modified with fluorophores and other markers.
Rp-8-CPT-cAMPS is an analog of Rp-cAMPS and a competitive inhibitor of protein kinase A type I and II (cAMP antagonist). It effects against mammalian cyclic nuc...
c-(ApIp) is a hybrid cyclic dinucleotide consisting of a 5'-AMP and a 5'-IMP unit.
2'-O-MB-cCMP is a precursor and biologically inactive analogue of cCMP, the putative second messenger nucleotide. cCMP would be released when 2'-O-MB-cCMP is me...
c-(Ap-8-AET-Gp) is an analogue of messenger c-(ApGp), the bacterial second, which is used as a ligand for affinity chromatography or for coupling of labelling s...
Sp-8-AEA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatogra...
8-APT-cGMP is an isozyme-selective stimulator of cGMP-dependent protein kinase I a with a prenference for type I a over I by a factor of 200.
2'-AHC-cGMP-Agarose is the protein kinase G activator cGMP immobilized on agarose by an aminohexylcarbamoyl spacer which can be used in affinity chromatography ...
Sp-c-diAMPS is an analogue of c-diAMP, the bacterial second messenger.
Rp-8-Br-PET-cGMPS is a selective inhibitor of cGMP-dependent protein kinase I a and I β and of retinal cGMP-gated ion channels. It effects against mammalian cyc...
Rp-2-Cl-cAMPS is an analogue of Rp-cAMPS, the protein kinase A inhibitor. The chlorine atom in position 2 of adenine nucleobase significantly increase the stabi...
Sp-8-Br-cAMPS-AM is a PDE-resistant precursor of Sp-8-Br-cAMPS, the protein kinase A stimulator. The active analogue is released after the metabolism of Sp-8-Br...
2'-AEC-cAMP is a ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers.
2'-F-dcAMP is an analogue of cAMP, which is a protein kinase A inactive agent.
Sp-6-Bnz-cAMPS is a selective and PDE-resistant stimulator of cAMP-dependent protein kinase, which can be used as an Epac-negative control.