|Molecular Formula||C27H38N12O14P2 (free acid)|
|Molecular Weight||816.6 (free acid)|
|Description||c[3'-AHC-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which can be used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores.|
|Purity||≥ 95% by HPLC|
|Synonyms||Cyclic (3'- O- (6- aminohexylcarbamoyl)guanosine- (2' −≥ 5')- monophosphate- adenosine- (3' −≥ 5')- monophosphate), sodium salt|
8-Cl-cAMP-AM is a precursor of 8-Cl-cAMP, the PKA activator. The polar active analogue is released after the metabolism of 8-Cl-cAMP-AM by esterases.
8-OH-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It can be used in patc...
2'-Biotin-16-c-diGMP is an analogue of c-diGMP. It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays.
Rp-cCMPS is a PDE-resistant cCMP, the potential second messenger, which inhibits cCMP-binding proteins.
Rp-8-AET-cGMPS is a ligand in affinity chromatography and can be modified with fluorophores or other markers.
Sp-8-AET-cGMPS-Agarose is the protein kinase G activator Sp-cGMPS immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatograp...
Sp-6-Phe-cAMPS is a selective and PDE-resistant stimulator of protein kinase A, which is used as an Epac-negative control.
Sp-8-AET-cGMPS is a ligand in affinity chromatography and can be modified with fluorophores or other markers.
Rp-8-pCPT-PET-cGMPS is an inhibitor of protein kinase G and probably of retinal cGMP-gated ion channels. It has a resistant against mammalian cyclic nucleotide-...
ara-cAMP is an analogue of cAMP, the second messenger. It is commonly used in receptor mapping studies and negative controls.
Sp-2-Cl-cAMPS is an analogue of Sp-cAMPS, the protein kinase A stimulator. The chlorine atom in position 2 of adenine nucleobase significantly increase the stab...
8-AHA-2'-O-Me-cAMP-Agarose is the second messenger cAMP with a methylated ribose 2'-hydroxy group immobilized on agarose by an aminohexylamino spacer, which can...
8-AET-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used as a ligand for affinity chromatography or for coupling of labelling ...
2',2''-Di-F-c-didAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used to study ligand-receptor interactions.
2'-O-Me-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which can be used to study ligand-receptor interactions.
8-Br-PET-cGMP is a stimulator of isozymes I α and I β of cGMP-dependent protein kinase, which is used as an excellent cyclic nucleotide muscle relaxants.
Sp-8-Cl-cAMPS is a resistant stimulator of protein kinase A, the cAMP agonist. Compared with 8-Cl-cAMP, it has the increased lipophilic and membrane-permeant pr...