|Description||Butylphthalide is an anti-cerebral-ischemia drug, which is first isolated from the seeds of celery, showed efficacy in animal models of stroke. It alleviates oxidative stress caused by chronic cerebral ischemia, improves cholinergic function, and inhibits amyloid beta accumulation, thereby improving cerebral neuronal injury and cognitive deficits.|
An inhibitor of 5α-reductase
Ac9-25 is a N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. It stimulates neutrophil NADPH oxidase activation by acting...
2-Aminoheptane, a fatty Amine compound, is commonly used in proteomics research and could also be used to product some A3 adenosine receptor antagonists.
PTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor.
CFI-400936 is a selective proteine kinase TTK inhibitor with IC50 value of 3.6nM. It demonstrates good activity in cell based assay and selectivity against a pa...
CGP 55802A has been found to be a photoaffinity ligand that could be used to label NMDA receptor and have high selectivity to glutamate recognition site.
Panaxadiol, a triterpenoid compound extracted from roots of Panax ginseng C, a novel antitumor agent that regulates of cell cycle transition and induces apoptot...
Isopropamide is a long-acting anticholinergic drug. It can be used for the treatment of peptic ulcers and other gastrointestinal disorders including hyperacidit...
(RS)-4-Carboxyphenylglycine has been found to be a broad spectrum EAA ligand.
Bloom (BLM) helicase is a DNA unwinding enzyme important for DNA repair in the homologous recombination pathway. Mutations of the BLM gene result in reduced BLM...
Dextrose, a simple sugar (monosaccharide), is an important carbohydrate in biology.
Nanofin is neuropathic blocker used for mild to moderate hypertension.
Benflumetol, also known as HSDB 7210, is an antimalarial drug used to treat acute uncomplicated malaria. It is used in combination with Artemether for improved ...
Torsemide is a pyridine-sulfonyl urea type loop diuretic with an IC50 of 2.7 ± 0.17 μM.
β-NADPH tetra (cyclohexylammonium) salt
β-NADPH tetra(cyclohexylammonium), generating in vivio by the pentose phosphate pathway, is a a ubiquitous cofactor and biological reducing agent.
PX-12 is an irreversible inhibitor of Trx-1 currently in clinical development as an antitumor agent. The research results suggest that the lowering of elevated ...
PROTO-1, a benzothiophene carboxamide, shows significant protection of hair cells over a broad range of neomycin concentrations, from 25 μM to 400 μM.
GKT137831 attenuates hypoxia-induced H(2)O(2) release, cell proliferation, and TGF-β1 expression and blunted reductions in PPARγ in HPAECs and HPASMCs.
Chitinase-IN-1 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20uM compound concentration's inhibitory percentage are 75%...