|Description||Butoconazole nitrate is an anti-fungal agent for IL-2, TNFα, IFN and GM-CSF with IC50 of 7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL and 7.6 μg/mL, respectively.|
Ascomycin, isolated from Streptomyces, suppresses immune response in vitro with IC50 of 0.55 nM for mouse mixed lymphocyte.
Voriconazole inhibits 95% of isolates at ≤1 μg/ml against 448 recent clinical mold isolates
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff and eczema. Climbazole has shown a high...
In a mouse model of septic A. fumigatus infection, although non-treated mice survived for a maximum of only 6 days, the survival rate of micafungin-treated mice...
Fluconazole (hydrate) is the hydrate salt form of fluconazole, which is a triazole antifungal intended for oral treatment of superficial and systemic mycoses. I...
The combination of Flucytosine and IgGl monoclonal antibody to Cryptococcus neoformans capsular glucuronoxylomannan is more effective in reducing the numbers of...
Etoxazole is a narrow spectrum systemic acaricide used to combat spider mites.
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast, with an average IC50 of 1.7 μM.
Terbinafine HCl is a hydrochloride salt of terbinafine that is a synthetic allylamine antifungal and a squalene epoxidase inhibitor with an IC50 of 30 nM for Ca...
Thifluzamide, a highly potent fungicide, could be commonly used in potatoes and rice against basidiomycete fungi.
Griseofulvin, a production from some strains of the mold Penicillium griseofulvumam, is able to inhibit cell mitosis by interfering with microtubule function.
Isavuconazole is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical imp...
Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking st...
Hexetidine, mixture of stereoisomers, is an antibacterial and antifungal agent that destroy fungi by suppressing their ability to grow or reproduce.
Fenticonazole Nitrate is an azole antifungal agent.
Caspofungin acetate is the first in a new class of antifungals that inhibits the synthesis of beta (1, 3)-d-glucan, an essential component of the cell wall of f...
Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.
Anidulafungin, is a semisynthetic echinocandin that inhibits glucan synthase, an enzyme important in the formation of (1→3)-β-D-glucan, a major fungal cell wall...
Pneumocandin B0, also called as L 688786, is an inhibitor of ß-(1,3)-D-glucan (a component of fungal cell walls) synthesis with an antifungal effect (IC50s = 70...
Liranaftate is a squalene epoxidase inhibitor exhabing anti-fungicidal activities.