|Description||BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. It may represent a valuable tool to selectively inhibit mitochondrial F1 Fo-ATPase activity without compromising ATP synthesis and to limit ischaemia-induced injury caused by reversal of the mitochondrial F1 Fo-ATPsynthase.|
Y16 is an inhibitor of G-protein–coupled Rho GEFs. It specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways and blocks the growth ...
FR-167356, a benzofuran derivative, has been found to be an acuolar ATPase inhibitor and could probablye be useful in studies of some lytic bone diseases.
BRITE 338733 is a novel ATPase inhibitor. BRITE 338733 inhibits the expression of RecA in bacteria (IC50=4.7 µM) for the treatment of bacterial infections.
CID 1067700 is a Rab7 GTPase inhibitor exhibiting significant inhibitory potency against Rab7 nucleotide binding with nanomolar inhibitor (Ki) values and an inh...
NSC 23766 (trihydrochloride)
NSC 23766 is a Rac GTPase inhibitor that suppresses Rac GTPase activation by the Rac-specific GEFs. It shows an inhibitory activity in the influenza virus, as w...
Rhosin is a specific Rho inhibitor, which binds to WT RhoA with an affinity ~0.4 μM Kd and does not interfere with the binding of Cdc42 or Rac1.
ML241 is a selective p97 ATPase inhibitor and IC50 value is 100 nM. It can inhibit degradation of a p97-dependent but not a p97-independent proteasome substrate...
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. It may represent a valuable tool to selectively inhibit mitochondrial F1 F...
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contract...
Rho GTPase inhibitor (Kd = 354 nM). Inhibits binding of RhoA to guanine nucleotide exchange factors (GEFs) including LARG, DBL, LBC, p115 RhoGEF and PDZ RhoGEF....