BS-181 HCl - CAS 1397219-81-6
Catalog number: B0084-463412
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C22H32N6.HCl
Molecular Weight:
416.99
COA:
Inquire
Targets:
CDK
Description:
BS-181 HCl is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-463412 50 mg $688 In stock
Bulk Inquiry
Purity:
>98%
Synonyms:
BS-181 HCl; BS 181 HCl; BS181 HCl
MSDS:
Inquire
InChIKey:
NVIJWMOQODWNFN-UHFFFAOYSA-N
InChI:
InChI=1S/C22H32N6.ClH/c1-17(2)19-16-26-28-21(25-15-18-10-6-5-7-11-18)14-20(27-22(19)28)24-13-9-4-3-8-12-23;/h5-7,10-11,14,16-17,25H,3-4,8-9,12-13,15,23H2,1-2H3,(H,24,27);1H
Canonical SMILES:
CC(C)C1=C2N=C(C=C(N2N=C1)NCC3=CC=CC=C3)NCCCCCCN.Cl
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related CDK Products


CAS 118458-54-1 Arcyriaflavin A

Arcyriaflavin A
(CAS: 118458-54-1)

Arcyriaflavin A is a potent dual target agent of calcium/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 4 (CDK4). Its IC50 values a...

CAS 802539-81-7 Milciclib

Milciclib
(CAS: 802539-81-7)

Milciclib is an orally bioavailable inhibitor of cyclin-dependent kinases (CDKs) and thropomyosin receptor kinase A (TRKA), with potential antineoplastic activi...

CAS 1092443-52-1 BS181

BS181
(CAS: 1092443-52-1)

BS-181 is a highly selective CDK inhibitor for CDK7 with an IC(50) of 21 nmol/L. Testing of other CDKs as well as another 69 kinases showed that BS-181 only inh...

CAS 718630-59-2 PHA-793887

PHA-793887
(CAS: 718630-59-2)

PHA-793887 is an inhibitor of multiple cyclin dependent kinases (CDK) with activity against CDK2, CDK1 and CDK4. Although toxicity was acceptable at initial dos...

CAS 1619903-54-6 LY2857785

LY2857785
(CAS: 1619903-54-6)

LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result i...

BS 181 dihydrochloride

BS 181 dihydrochloride is a selective CDK7 inhibitor (IC50 = 21 nM) displaying >40-fold selectivity for CDK7 over others CDKs. BS 181 promotes cell cycle arrest...

CAS 602306-29-6 AZD5438

AZD5438
(CAS: 602306-29-6)

AZD5438 is a potent inhibitor of cyclin-dependent kinase (cdk) 1, 2, and 9 (IC(50), 16, 6, and 20 nmol/L, respectively). Broad cdk inhibition may provide an eff...

CAS 1453834-21-3 LDC4297

LDC4297
(CAS: 1453834-21-3)

LDC4297 is a potent and selective cyclin-dependent protein kinase 7 (CDK7) inhibitor with an IC50 of 0.13 nM.

Chemical Structure

CAS 1397219-81-6 BS-181 HCl

Quick Inquiry

Verification code

Featured Items