|Description||Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.|
|Solubility||Water and saline buffer|
|Storage||Stable in freeze-dried state; keep in dark and cold place; in solution, keep at -20 °C.|
An inhibitor of MAO.
an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibits microtubule assembly.
Anti-tumor effect of hernandezine and other components extracted from Thalictrum glandulosissimum.
A hypolipidemic, antiatherosclerotic, anti-inflammatory agent, with angioprotective and hepatoprotective activity; antiulcerous. Sesquiterpene lactone , from pl...
Alkaloid from reticuline and is a precursor of berberine.It has also been found to be a GABAA receptor agonist.
Fraxinellone is an insecticidal agent, inhibiting growth of larvae, used in the treatment and protection of crops and produce. Also, a naturally occurring compo...
Extractedfrom Vinca erecta. A dopamine receptor stimulating agent Indolinine alkaloid
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
Taltobulin trifluoroacetate (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
Artemisinin is a natural product originally isolated from plants of the genus Artemisia. It effectively kills malarial parasites of the genus Plasmodium. It is ...
Alkaloid, extracted from Thalictrum isopyroide.
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
A highly active peripheral M2-cholinoblocker alkaloid. Imperialine is extracted from Petilium eduardi and Petilium raddeanae (Liliaceae family)
Estrogenic activity; half agonist of estradiol receptors. Complex esters of phenolcarbon acids, , from plants of the Ferula genus, Umbelliferae.
Sesquiterpene lactone , from plants of the Compositae family, an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.
An analog of Veratridine; Na+ channel activator; potent neurotoxic; depolarizing agent on membranes of nerve terminal, muscle and gland cells.
A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and ...
Polyprenols are natural long-chain isoprenoid alcohols of the general formula H-(C5H8)n-OH where n is the number of isoprene units. Any prenol with more than 4 ...