|Description||Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.|
|Solubility||Water and saline buffer|
|Storage||Stable in freeze-dried state; keep in dark and cold place; in solution, keep at -20 °C.|
Dihydropyridine calcium channel blocker. Antianginal; antihypertensive.
Synthetic, a selective irreversible inhibitor of carboxylesterases
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An antiarrhythmic of 1-st and 1Y classes and a blocker of TTX sensitive Na+ channels, Ca++ antagonist diterpene alkaloid from Delphinium staphisagria.
α-conotoxin MI (alpha-conotoxin MI) is a conotoxin that has been isolated from the venom of the cone snail Conus magus. α-conotoxin MI is a competitive antagoni...
Triterpene glycoside Extracted from Dipsacus azureas
a nicotinic cholinoreceptor antagonist at the neuromuscular junction; curare-like ganglioblocker. Bis-quaternary quinuclidine derivative, , synthetic.
Ducamycin Analog is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.