BRD7116 - CAS 329059-55-4
Catalog number:
329059-55-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C28H36N2O4S
Molecular Weight:
496.66
COA:
Inquire
Targets:
DNA/RNA Synthesis
Description:
BRD7116, a bis-aryl sufone with cell-non-autonomous anti-leukemia activity, competitively binds to bacterial DNA gyrase and is an inhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM) but does not affect normal hematopoietic stem cells or AML cel
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Appearance:
Solid powder
Synonyms:
2,2,3,3-tetramethyl-N-[4-[4-[(2,2,3,3-tetramethylcyclopropanecarbonyl)amino]phenyl]sulfonylphenyl]cyclopropane-1-carboxamide BRD7116 329059-55-4 BRD7716 ZINC00626297
Solubility:
Soluble to ≥ 48 mg/mL in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -97℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Boiling Point:
681.1±40.0 °C | Condition: Press: 760 Torr
Density:
1.193±0.06 g/cm3
InChIKey:
UHXFWAHRAMUDLJ-UHFFFAOYSA-N
InChI:
1S/C28H36N2O4S/c1-25(2)21(26(25,3)4)23(31)29-17-9-13-19(14-10-17)35(33,34)20-15-11-18(12-16-20)30-24(32)22-27(5,6)28(22,7)8/h9-16,21-22H,1-8H3,(H,29,31)(H,30,32)
Canonical SMILES:
CC1(C(C1(C)C)C(=O)NC2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)C4C(C4(C)C)(C)C)C
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