Bradanicline hydrochloride - CAS 1111941-90-2
Catalog number: 1111941-90-2
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C22H24ClN3O2
Molecular Weight:
397.90
COA:
Inquire
Targets:
nAChR
Description:
Bradanicline hydrochloride is Alpha-7 Nicotinic Receptor Agonist. It showed cognitive enhancing effects in animal studies, and was being developed as a potential treatment for schizophrenia and attention deficit disorder. It was discontinued for Alzheimer's disease and cognitive impairment in schizophrenia in late 2013. It was also discontinued for ADHD, and no longer seems to be being developed.
Purity:
>98%
Appearance:
Solid powder
Synonyms:
TC-5619;TC5619;TC-5619-023;TC5619-023;N-((2S,3R)-2-(pyridin-3-ylmethyl)quinuclidin-3-yl)benzofuran-2-carboxamide hydrochloride
Solubility:
10 mM in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Bradanicline hydrochloride was being developed as a potential treatment for schizophrenia and attention deficit disorder.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
ISPRRZDPZDVHLE-OZYANKIXSA-N
InChI:
InChI=1S/C22H23N3O2.ClH/c26-22(20-13-17-5-1-2-6-19(17)27-20)24-21-16-7-10-25(11-8-16)18(21)12-15-4-3-9-23-14-15;/h1-6,9,13-14,16,18,21H,7-8,10-12H2,(H,24,26);1H/t18-,21+;/m0./s1
Canonical SMILES:
C1CN2CCC1C(C2CC3=CN=CC=C3)NC(=O)C4=CC5=CC=CC=C5O4.Cl
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