BQCA - CAS 338747-41-4
Catalog number:
338747-41-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C18H15NO4
Molecular Weight:
309.32
COA:
Inquire
Targets:
mAChR
Description:
BQCA is a highly selective positive allosteric modulator of the M1 muscarinic acetylcholine receptor (mAChR), as it dose-dependently reduces the concentration of acetylcholine required to activate the M1 receptor.
Publictions citing BOC Sciences Products
  • >> More
Purity:
≥98%
Appearance:
White to beige powder
Synonyms:
1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; 1,4-Dihydro-1-[(4-methoxyphenyl)methyl]-4-oxo-3-quinolinecarboxylic Acid
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
A highly selective positive allosteric modulator of the M1 muscarinic acetylcholine receptor (mAChR)
Quality Standard:
Enterprise standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.
Quantity:
Milligrams-Grams
InChIKey:
BZBBTGCKPRSPGF-UHFFFAOYSA-N
InChI:
1S/C18H15NO4/c1-23-13-8-6-12(7-9-13)10-19-11-15(18(21)22)17(20)14-4-2-3-5-16(14)19/h2-9,11H,10H2,1H3,(H,21,22)
Canonical SMILES:
COC1=CC=C(CN2C(C=CC=C3)=C3C(C(C(O)=O)=C2)=O)C=C1
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related mAChR Products


CAS 171722-81-9 YM-46303

YM-46303
(CAS: 171722-81-9)

YM-46303 is an mAChR antagonist which had a binding affinity of 0.39 nM to M3-receptors. YM-46303 exhibits the highest affinities for M1 and M3 receptors. YM-46...

CAS 136310-93-5 Tiotropium bromide

Tiotropium bromide
(CAS: 136310-93-5)

Tiotropium Bromide, an azoniatricyclo derivative, is a mAChR antagonist that could be used as bronchodilation agent and smooth muscle relaxant.

CAS 286930-03-8 Fesoterodine Fumarate

Fesoterodine Fumarate
(CAS: 286930-03-8)

Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor...

CAS 26095-59-0 Otilonium Bromide

Otilonium Bromide
(CAS: 26095-59-0)

Otilonium Bromide is an antimuscarinic used as a spasmolytic agent.

CAS 1098-97-1 Pyrithioxin

Pyrithioxin
(CAS: 1098-97-1)

Pyrithioxin, a pyridine thiol derivatives, could be used in the treatment of traumatic brain injury sequelae and some sorts of cerebral infarct patients with He...

CAS 101-31-5 Hyoscyamine

Hyoscyamine
(CAS: 101-31-5)

Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.

CAS 139404-48-1 Tiotropium Bromide hydrate

Tiotropium Bromide hydrate
(CAS: 139404-48-1)

Tiotropium Bromide hydrate is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a mus...

CAS 5908-99-6 Atropine sulfate salt monohydrate

Atropine sulfate salt monohydrate
(CAS: 5908-99-6)

Atropine is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 2.5 nM.

CAS 10405-02-4 Trospium chloride

Trospium chloride
(CAS: 10405-02-4)

Trospium chloride is a competitive muscarinic cholinergic receptor antagonist.

CAS 124937-52-6 Tolterodine tartrate

Tolterodine tartrate
(CAS: 124937-52-6)

Tolterodine has a high affinity and specificity for muscarinic receptors in vitro and it exhibits selectivity for the urinary bladder over salivary glands in vi...

CAS 409351-28-6 VU0152100

VU0152100
(CAS: 409351-28-6)

VU0152100 is a selective and positive allosteric modulators of M4 receptor. It has shown a potent positive allosteric modulators that increase the response of t...

CAS 113-69-9 Benzquinamide Hydrochloride

Benzquinamide Hydrochloride
(CAS: 113-69-9)

Benzquinamide hydrochloride is an antiemetic compound with antihistaminic, anticholinergic and sedative properties. The mechanism of action is not quite sure an...

CAS 514-65-8 Biperiden

Biperiden
(CAS: 514-65-8)

Biperiden is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. It is used for the adjunctive treatment of all forms of Park...

CAS 6989-98-6 Tubocurarine hydrochloride pentahydrate

Tubocurarine hydrochloride pentahydrate
(CAS: 6989-98-6)

Tubocurarine is a toxic alkaloid. It is an acetylcholine receptor (AChR)-blocking agent. Tubocurarine is now rarely used as an adjunct for clinical anesthesia b...

CAS 77-19-0 Dicycloverine (Dicyclomine)

Dicycloverine (Dicyclomine)
(CAS: 77-19-0)

Dicycloverine, also known as dicyclomine, is an anticholinergic that blocks muscarinic receptors.

CAS 1508-65-2 Oxybutynin chloride

Oxybutynin chloride
(CAS: 1508-65-2)

Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.

CAS 54-71-7 Pilocarpine Hydrochloride

Pilocarpine Hydrochloride
(CAS: 54-71-7)

Pilocarpine HCl is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy.

CAS 62-97-5 Diphemanil Methylsulfate

Diphemanil Methylsulfate
(CAS: 62-97-5)

Diphemanil Methylsulfate is a quaternary ammonium anticholinergic.It binds muscarinic acetycholine receptors (mAchR).

CAS 1227923-29-6 MK-7622

MK-7622
(CAS: 1227923-29-6)

MK-7622 is a cholinesterase inhibitor under evaluation for the treatment of Alzheimer's disease. No studies have been published on this compound in the peer-rev...

CAS 68252-19-7 Pirmenol

Pirmenol
(CAS: 68252-19-7)

Pirmenol, also known as CI-845, a new antiarrhythmic drug, inhibits muscarinic acetylcholine receptor-operated K+ current in the guinea pig heart. However, pirm...

Quick Inquiry

Verification code

Featured Items