BPO-27 racemate - CAS 1314873-02-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C26H18BrN3O6
Molecular Weight:
548.34
COA:
Inquire
Targets:
CFTR
Description:
BPO-27 racemate inhibited CFTR with IC50 ≈ 8 nM and had greatly improved in vitro metabolic stability and aqueous solubility compared to PPQ-102.
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Brife Description:
A potent CFTR inhibitor (IC50= 8 nM)
Synonyms:
BPO-27 (racemate); CHEMBL1831075; BPO-27 racemat
Solubility:
DMSO: 6 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
732.9±70.0 ℃ at 760 Torr
Density:
1.68±0.1 g/cm3
InChIKey:
GNHIGSRGYXEQEP-UHFFFAOYSA-N
InChI:
1S/C26H18BrN3O6/c1-28-21-19(24(31)29(2)26(28)34)20(13-6-4-3-5-7-13)30-15-12-14(25(32)33)8-9-16(15)36-23(22(21)30)17-10-11-18(27)35-17/h3-12,23H,1-2H3,(H,32,33)
Canonical SMILES:
CN1C2=C3C(OC4=C(N3C(=C2C(=O)N(C1=O)C)C5=CC=CC=C5)C=C(C=C4)C(=O)O)C6=CC=C(O6)Br
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