|Targets||5-HT Receptor | Sigma Receptor|
|Description||BMY 14802 hydrochloride is a potent sigma receptor antagonist (IC50 = 112 nM) with weak affinity for 5-HT1A and α1 receptors. BMY 14802 is potentially used as an atypical antipsychotic agent for schizophrenia treatment.|
|Brife Description||sigma receptor antagonist|
|Purity||≥98% by HPLC|
|Related CAS||105565-56-8 (free base)|
|Synonyms||BMS-181100 hydrochloride; BMY 14802 HCl; α-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol hydrochloride|
|Application||potential atypical antipsychotic agent|
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ST 1936 oxalate
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BMY 14802 hydrochloride
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α-Methyl-5-hydroxytryptamine maleate, a salt of α-Methylserotonin maleate, is a 5-HT2B receptor selective agonist with pKi values of 8.4, 6.1 and 7.3 at 5-HT2B,...
Zatosetron has been identified as a potent, orally available, long-acting, selective 5HT3 receptor antagonist, which is potentially useful in the treatment of c...
MK212 hydrochloride is a selective 5-HT2C serotonin receptor agonist. It displays selectivity for 5-HT2C over 5-HT2A with IC50 values of 0.028 and 0.42 μM for h...
PU 02 is a potent and selective 5-HT3 receptor antagonist (IC50 values are 0.36 and 0.73 μM in HEK293 cells transfected with human 5-HT3A and 5-HT3AB receptors ...
PB 28 dihydrochloride
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Tegaserod maleate is a partial agonist of the 5-HT4 receptor (Ki = 12 nM) that can treat irritable bowel syndrome (IBS).