BMX-IN-1 - CAS 1431525-23-3
Catalog number:
1431525-23-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C29H24N4O4S
Molecular Weight:
524.59
COA:
Inquire
Targets:
BMX Kinase
Description:
BMX-IN-1 selectively and irreversibly inhibits BMX (IC50=8nM) that is significant for ischemia-mediated arteriogenesis and lymphangiogenesis regulation. It also inhibits the proliferation of RV-1 (GI50s=2.54µM), DU-145 (GI50s=4.38µM), PC-3 (GI50s=5.37nM),
Publictions citing BOC Sciences Products
  • >> More
Appearance:
Solid powder
Synonyms:
N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[h][1,6]naphthyridin-1-yl]-2-methylphenyl]prop-2-enamide BMX-IN-1 1431525-23-3 GTPL9269 SCHEMBL17052523 BDBM102620 CS-1295 HY-80002 Example 1-14 [ WO2014063054] W-6056 N-[5-[9-[4-(methanesulfonamido)phenyl]
Solubility:
Soluble to ~0.25 mg/ml in a 1:3 solution of DMSO:PBS (pH 7.2); ~30 mg/ml in DMSO; ~10 mg/ml in DMF
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -42℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
Density:
1.397±0.06 g/cm3
InChIKey:
SFMJNHNUOVADRW-UHFFFAOYSA-N
InChI:
1S/C29H24N4O4S/c1-4-27(34)31-26-16-23(12-5-18(26)2)33-28(35)14-9-21-17-30-25-13-8-20(15-24(25)29(21)33)19-6-10-22(11-7-19)32-38(3,36)37/h4-17,32H,1H2,2-3H3,(H,31,34)
Canonical SMILES:
CC1=C(C=C(C=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CC=C(C=C5)NS(=O)(=O)C)NC(=O)C=C
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related BMX Kinase Products


BMX-IN-1
(CAS: 1431525-23-3)

BMX-IN-1 selectively and irreversibly inhibits BMX (IC50=8nM) that is significant for ischemia-mediated arteriogenesis and lymphangiogenesis regulation. It also...

CAS 1808288-51-8 CHMFL-BMX-078

CHMFL-BMX-078
(CAS: 1808288-51-8)

CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor that exhibits an IC50 of 11 nM against BMX kinase and exhibits great se...

Quick Inquiry

Verification code

Featured Items