BMS711939 - CAS 1000998-62-8
Catalog number:
1000998-62-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H20ClFN2O6
Molecular Weight:
462.86
COA:
Inquire
Targets:
Others
Description:
BMS711939 is a selective and potent peroxisome proliferator-activated receptor α(PPARα) agonist with EC50 value of 4 nM for human PPARα. It is >1000-fold selectivity vs human PPARγ with EC50 value of 4.5 μM and PPARδ with EC50 value of > 100 μM in PPAR-GAL4 transactivation assays. It shows excellent in vivo efficacy and safety profiles in preclinical studies. It was chosen for further preclinical evaluation.
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Purity:
>98 %
Appearance:
Solid powder
Synonyms:
Glycine, N-((5-((2-(4-chlorophenyl)-5-methyl-4-oxazolyl)methoxy)-2-fluorophenyl)methyl)-N-(methoxycarbonyl)-; BMS-711939;2-[[5-[[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy]-2-fluorophenyl]methyl-methoxycarbonylamino]acetic acid
Solubility:
10 mM in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
BMS711939 was chosen for further preclinical evaluation.
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Melting Point:
650.1±65.0 °C | Condition: Press: 760 Torr
Density:
1.379±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
OPHWZEQODBXRCZ-UHFFFAOYSA-N
InChI:
InChI=1S/C22H20ClFN2O6/c1-13-19(25-21(32-13)14-3-5-16(23)6-4-14)12-31-17-7-8-18(24)15(9-17)10-26(11-20(27)28)22(29)30-2/h3-9H,10-12H2,1-2H3,(H,27,28)
Canonical SMILES:
CC1=C(N=C(O1)C2=CC=C(C=C2)Cl)COC3=CC(=C(C=C3)F)CN(CC(=O)O)C(=O)OC
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