|Description||BMS694153 is a potent and selective calcitonin gene-related peptide(CGRP) receptor antagonist. It is related with the pathogenesis of migraine.|
|Solubility||10 mM in DMSO|
|Application||BMS694153 is related with the pathogenesis of migraine.|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Boiling Point||936.5±65.0 °C | Condition: Press: 760 Torr|
|Density||1.316±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
BMS694153 is a potent and selective calcitonin gene-related peptide(CGRP) receptor antagonist. It is related with the pathogenesis of migraine.
SB 268262 is a selective and non-peptide calcitonin gene-related peptide (CGRP1) receptor antagonist. SB 268262 inhibits [125I]CGRP binding and CGRP-activated a...
Olcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with 150-fold select...
MK-3207 is a orally active and potent calcitonin gene-related peptide (CGRP) receptor antagonist IC50 vaule of 0.12 nM and Ki value of 0.024 nM. It is highly se...
CGRP 8-37 (human)
CGRP 8-37 (human) is a peptide antagonist for CGRP1 receptors.
Amylin, islet Amyloid Polypeptide (IAPP), is a 37-residue peptide hormone secreted by pancreatic β-cells. It inhibits insulin-stimulated glucose uptake, delays ...
Telcagepant is a calcitonin gene-related peptide(CGRP) receptor antagonist under development for the acute treatment and prevention of migraine. It is a highly ...
Rimegepant, a CGRP receptor antagonist, has been found to have potential effect against Migraine by Bristol-Myers Squibb. The Phase II trial of it has already b...
Olcegepant, also called as BIBN4096BS or BIBN 4096, is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) re...
CGRP 8-37 (rat)
CGRP 8-37 (rat) is a peptide antagonist for CGRP1 receptors.
α-CGRP (rat) is an endogenous neuropeptide displaying vasodilator, cardiovascular, pro-inflammatory and metabolic effects.
Amylin (rat), islet Amyloid Polypeptide (IAPP), is a glucoregulatory peptide from rat pancreatic cells. It inhibits glucagon secretion, delays gastric emptying ...
MK-3207 is a potent CGRP receptor antagonist with IC50 and Ki of 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3.
α-CGRP (human) is an endogenous calcitonin gene-related peptide receptor (CGRP) agonist.
Ubrogepant is and selective oral calcitonin gene-related peptide (CGRP) receptor antagonist originated by Merck & Co. In Sep 2016, Allergan initiated a phase II...