BMS561392 - CAS 611227-74-8
Catalog number: 611227-74-8
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C27H32N4O4
Molecular Weight:
476.57
COA:
Inquire
Targets:
TNF-alpha
Description:
BMS561392 is a tumor necrosis factor-alpha (TNF alpha) converting enzyme inhibitor. It has the potential treatment of diseases characterized by overproduction of TNF alpha, such as rheumatoid arthritis (RA). It was developed by Bristol-Myers Squibb and was in clinic phase 2 trials, but now it is terminated.
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Purity:
98%
Appearance:
Solid powder
Synonyms:
(αR,​3R)​-3-​Amino-​N-​hydroxy-​α-​(2-​methylpropyl)​-​3-​[4-​[(2-​methyl-​4-​quinolinyl)​methoxy]​phenyl]​-​2-​oxo-​1-​pyrrolidineacetamide​;BMS-561392;DPC-333;(2R)-2-[(3R)-3-amino-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]-2-oxopyrrolidin-1-yl]-N-hyd
Solubility:
Soluble in DMSO, not in water
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
BMS561392 has the potential treatment of diseases characterized by overproduction of TNF alpha, such as rheumatoid arthritis (RA).
Quality Standard:
In-house standard
Quantity:
Milligrams-Grams
Density:
1.253±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
QVNZBDLTUKCPGJ-SHQCIBLASA-N
InChI:
InChI=1S/C27H32N4O4/c1-17(2)14-24(25(32)30-34)31-13-12-27(28,26(31)33)20-8-10-21(11-9-20)35-16-19-15-18(3)29-23-7-5-4-6-22(19)23/h4-11,15,17,24,34H,12-14,16,28H2,1-3H3,(H,30,32)/t24-,27-/m1/s1
Canonical SMILES:
CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)C4(CCN(C4=O)C(CC(C)C)C(=O)NO)N
Current Developer:
BMS561392 was developed by Bristol-Myers Squibb and was in clinic phase 2 trials, but now it is terminated.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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