|Description||BMS561392 is a tumor necrosis factor-alpha (TNF alpha) converting enzyme inhibitor. It has the potential treatment of diseases characterized by overproduction of TNF alpha, such as rheumatoid arthritis (RA). It was developed by Bristol-Myers Squibb and was in clinic phase 2 trials, but now it is terminated.|
|Solubility||Soluble in DMSO, not in water|
|Application||BMS561392 has the potential treatment of diseases characterized by overproduction of TNF alpha, such as rheumatoid arthritis (RA).|
|Quality Standard||In-house standard|
|Density||1.253±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
|Current Developer||BMS561392 was developed by Bristol-Myers Squibb and was in clinic phase 2 trials, but now it is terminated.|
A potent, orally active and dual inhibitor of phosphodiesterase 4 (PDE4) (IC50= 1.1 μM) and tumor necrosis factor-α (TNF-α) (IC50= 2.5 μM).
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BMS561392 is a tumor necrosis factor-alpha (TNF alpha) converting enzyme inhibitor. It has the potential treatment of diseases characterized by overproduction o...
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