|Description||BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent.|
Tenofovir alafenamide fumarate, also known as Tenofovir alafenamide hemifumarate; TAF, GS-7340, is a nucleotide reverse transcriptase inhibitor and a novel pro...
BMS-663749 is HIV-1 attachment inhibitor.
Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM. It is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is ...
PNU-104489, a sulfonamidoindol derivative, has been found to be a HIV-1 specific inhibitor and was proved to exhibit activity against BHA-P-resistant HIV-1MF ha...
Ritonavir is a very potent inhibitor of CYP3A4 mediated testosterone 6β-hydroxylation with mean Ki of 19 nM and also inhibits tolbutamide hydroxylation with IC5...
Stavudine (d4T) is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV.
AMD3465 is a potent and highly selective monomacrocyclic CXCR4 antagonist (IC50= 0.75 nM). It potently inhibits HIV cell entry in vitro and causes leukocytosis ...
Tenofovir blocks reverse transcriptase and hepatitis B virus infections.
Lopinavir is a potent HIV protease inhibitor with Ki of 1.3 pM.
D77 is anti-HIV-1 inhibitor, which inhibits HIV-1(IIIB) replication (EC50=23.8 μM)
Indinavir is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV infection and AIDS. It inhibits the HIV-1 protease wi...
Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy. It inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at saquinavir as a ...
BMS-663068 tris is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
Tipranavir, a nonpeptidic HIV protease inhibitor (NPPI), inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against mult...
Selective CCR5 antagonist
Abacavir sulfate is a Nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS.
Ebselen, also known as SPI-1005, is an organoselenium compound with potential anti-oxidant, anti-inflammatory and cytoprotective activity. Upon oral administra...
Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and repli...
NBD-556 is small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. The C...
Emtricitabine moderately reduces hepatocyte proliferation independent of effects on mtDNA in HepG2 human hepatoma cells.