|Description||BMS-243117 is a potent and selective Lck inhibitor with good cellular activity against T-cell proliferation. BMS-24311 has potential to treat diseases such as rheumatoid arthritis and asthma.|
|Synonyms||2-(tert-butylcarbamoylamino)-N-(2-chloro-6-methylphenyl)-1,3-benzothiazole-6-carboxamide; BMS-243117; UNII-MBE6KWV0QI|
Mastoparan, a tetradecapeptide which is a component of wasp venom, activates Gi and Go and has been shown to cause an increase in the production of Arachidonic ...
RuBi-Glutamate, a ruthenium-bipyridine-trimethylphosphine caged glutamate, can be excited by visible wavelengths and releases glutamate after one- or two- photo...
CB 3703 is an inhibitor of hydrofolate reductase.
Pyraclonil is a herbicide agent.
Anethole trithione is a antitumor agent used in the treatment of dry mouth
OAC1 is a Octamer-binding transcription factor 4 (Oct4)-activating compound; enhances the iPSC reprogramming efficiency and accelerated the reprogramming proces...
Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on. Taxifolin has shown to inhibit the ovarian cancer cel...
Resibufogenin influenced peak amplitude, overshoot and half-width of the evoked single action potential, and simultaneously lessened the firing rate of evoked r...
GNE-3511 has been found to be a DLK, MAP3K12 kinase inhibitor that could probably exhibit protection action of primary neurons. IC50: 0.107 uM (DLK).
GSK 4112, a kind of synthetic agonist of REV-ERBα, could suppress the expression of sorts of genes involved in gluconeogenesis. IC50: 0.4 μM (EC50).
VU 0463271 is a potent and selective inhibitor of KCC2, which is a neuronal K-Cl cotransporter (IC50 = 61 nM). VU 0463271 exhibits >100-fold selectivity versus ...
TC-S 7006 is a potent, selective and reversible Tpl2 (Cot; MAP3K8) inhibitor (IC50 = 50 nM) with selectivity for Tpl2 over MEK, p38, Src, MK2, PKC and EGFR. TC-...
Diacerin is an inhibitor of pro-inflammatory cytokine Interleukin-1B (IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis.
Pep 2-8 is a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor.
Gliquidone is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM.
Fludrocortisone, a kind of mineralocorticoid, could be used against cerebral salt wasting syndrome for behaving the role as a anti-inflammatory agent.
Foresaconitine is a norditerpenoid alkaloid isolated from the processed tubers of Aconitum carmichaeli.
NKH477 is a water-soluble analog of forskolin, which is an adenylyl cyclase activator, but it is sparingly soluble in aqueous solutions. It has both inotropic a...
MIRA-1 is a maleimide-derived compound that reactivates the tumor suppressor function of mutant p53. It can induce apoptosis in several human solid tumor cell l...
GSK2837808A is a potent and specific lactate dehydrogenase A (LDHA) with IC50values of 1.9 and 14 nM for LDHA and LDHB, respectively and inhibits lactate produc...