BMS-214662 mesylate - CAS 474010-58-7
Catalog number: 474010-58-7
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H25N5O6S3
Molecular Weight:
585.72
COA:
Inquire
Targets:
Others
Description:
BMS-214662 mesylate is a potent and selective inhibitor of farnesyltransferase that induces mitochondrial apoptosis in chronic myeloid leukemia stem/progenitor cells, including CD34+38- cells, through activation of protein kinase Cβ.
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Purity:
≥98%
Appearance:
Light Yellow Solid
Synonyms:
(R)-2,3,4,5-Tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-Benzodiazepine-7-carbonitrile monohydrochloride, (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine mesylate
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
A potent and selective inhibitor of farnesyltransferase
Quality Standard:
Enterprise standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.
Quantity:
Milligrams-Grams
InChIKey:
GQZSWQUMYWWKTN-GNAFDRTKSA-N
InChI:
1S/C25H23N5O2S2.CH4O3S/c26-13-20-8-9-24-21(11-20)15-30(34(31,32)25-7-4-10-33-25)23(12-19-5-2-1-3-6-19)17-29(24)16-22-14-27-18-28-22;1-5(2,3)4/h1-11,14,18,23H,12,15-17H2,(H,27,28);1H3,(H,2,3,4)/t23-;/m1./s1
Canonical SMILES:
CS(=O)(=O)O.c1ccc(cc1)C[C@@H]2CN(c3ccc(cc3CN2S(=O)(=O)c4cccs4)C#N)Cc5cnc[nH]5
Current Developer:
Bristol-Myers Squibb
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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