Ginseng is any of eleven different varieties of short, slow growing perennial plants with fleshy roots. Ginseng is believed to restore and enhance normal well-being and has become one of the most popular herbal remedies in the world today.<\/p>\n
The following main ginseng health benefits\u00a0have been suggested:<\/p>\n
Ginseng may help with stimulating physical and mental activity among people who are weak and tired. The mental and energy boosts from ginseng are smooth and not like that from coffee.\u00a0Ginseng has been shown to reduce fatigue and increase energy in cancer patients. It\u2019s one of the more useful herbal remedies for chronic fatigue syndrome (CFS).<\/p>\n
Ginseng may improve thinking ability and cognition. Ginseng works as a brain booster and protector. It can improve mental performance and ability to concentrate. It also prevents memory loss, protects against age-related mental decline and improves memory in stroke patients.<\/p>\n
There may be substances in ginseng that have anticancer properties and protective against some kinds of cancer<\/a> including lung, liver, pancreatic, ovarian, and stomach cancers.<\/p>\n Ginseng species contains ginsenosides, polysaccharides, amino acids, peptides,\u00a0polyacetylenic alcohols and fatty acids. Growing evidence has demonstrated that these\u00a0components possess physiological effects in biological systems, in which\u00a0ginsenosides are the principal pharmacologically active component. More than thirty ginsenosides have been identified and are broadly classified into three categories: the 20(S<\/i><\/em>)-protopanaxadiol (PPD) (Rb1, Rb2, Rb3, Rc, Rd, Rg3, Rh2, Rs1), the\u00a020(S<\/i><\/em>)-protopanaxatriol (PPT) (Re, Rf, Rg1, Rg2, Rh1), and the oleanolic acid group\u00a0(Ro). Moreover, several rare ginsenosides, such as the ocotillol saponin F11 (24-R-pseudoginsenoside) and the pentacyclic oleanane saponin Ro (3,28-O-bisdesmoside) have also been identified.<\/p>\n Also, ginsenosides can be categorized into either pro-oxidative or anti-oxidative\u00a0according to structural configuration. Ginsenosides with no sugar\u00a0moieties attached to the C-20 position of the triterpene dammarane act as pro-oxidants\u00a0(e.g. Rg3, Rh2, and Rg2), while a mere glucose attached to the C-6 position, but not\u00a0C-20, rendered the ginsenoside an antioxidant (e.g. Rh1).<\/p>\n The adopted nomenclature of ginsenosides is\u00a0based on the distribution where \u201cR\u201d stands for the root and the chromatographic\u00a0polarity from the least polar to the most polar one alphabetically (i.e., \u201ca\u201d is less polar\u00a0than \u201cb\u201d and so forth). The content and composition of ginsenosides in ginseng can\u00a0vary depending on the species, age, cultivation methods, part of the plant,\u00a0preservation method, season of harvest, and extraction method. For examples, ginsenoside-Rg2 and -Rf\u00a0can only be found in the Asian ginseng and are absent from American ginseng.\u00a0Recently, ginsenoside-Ra1, -Ra2, -Ra3, -Rg4, -Rg5, -Rg6, -Rk1, -Rs1 and -Rs2 have\u00a0further been identified in the red ginseng. In Asia, red ginseng is more expensive than white\u00a0ginseng due to the presence of the additional ginsenosides and supposed better\u00a0medical efficacy.<\/p>\n Ginsenosides are triterpene saponins. Most ginsenosides are composed of a dammarane skeleton (17 carbons in a four-ring structure) with various sugar moieties (e.g. glucose, rhamnose, xylose and arabinose) attached to the C-3 and C-20 positions.\u00a0The extra hydroxyl group or sugar derivatives at the C-6 position\u00a0of the PPT defines the major structural difference from the PPD. Conformationally, all\u00a0ginsenosides have a flat core A-B-C-D fused ring. Thus, sugar substitutes on\u00a0ginsenosides neither collide with each other nor cause significant steric crowding. The\u00a0side-chain structures of ginsenosides are relatively flexible and are highly dependent\u00a0on the solvent and local environments.<\/p>\n Reference: Ginseng is any of eleven different varieties of short, slow growing perennial plants with fleshy roots. Ginseng is believed to restore and enhance normal well-being and has become one of […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bocsci.com\/blog\/wp-json\/wp\/v2\/posts\/649"}],"collection":[{"href":"https:\/\/www.bocsci.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bocsci.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bocsci.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bocsci.com\/blog\/wp-json\/wp\/v2\/comments?post=649"}],"version-history":[{"count":4,"href":"https:\/\/www.bocsci.com\/blog\/wp-json\/wp\/v2\/posts\/649\/revisions"}],"predecessor-version":[{"id":653,"href":"https:\/\/www.bocsci.com\/blog\/wp-json\/wp\/v2\/posts\/649\/revisions\/653"}],"wp:attachment":[{"href":"https:\/\/www.bocsci.com\/blog\/wp-json\/wp\/v2\/media?parent=649"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bocsci.com\/blog\/wp-json\/wp\/v2\/categories?post=649"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bocsci.com\/blog\/wp-json\/wp\/v2\/tags?post=649"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Related Products:<\/h4>\n
<\/th> <\/th> <\/th><\/tr><\/thead> CAS Number <\/td> Product Name <\/td> Description <\/td><\/tr> 41753-43-9 <\/td> Ginsenoside Rb1<\/a><\/td> Ginsenoside Rb1 shows anti-oxidative damage ,anti-renal interstitial fibrosis, immunostimulatory and anticancer effects. <\/td><\/tr> 11021-13-9 <\/td> Ginsenoside Rb2<\/a><\/td> Ginsenoside Rb2 is a 20(S)-protopanaxadiol glycoside extracted from ginseng. It shows potent antioxidant and anticancer biological activities. It inhibited invasiveness to the basement membrane of endometrial cancer cell lines Ishikawa. <\/td><\/tr> 11021-14-0 <\/td> Ginsenoside Rc<\/a><\/td> Ginsenoside Rc is a steroid glycoside, which is found exclusively in the plant genus Panax (ginseng). It has properties that inhibit or prevent tumors growth. It may have effects that prevent or limit the development of breast cancer. <\/td><\/tr> 52705-93-8 <\/td> Ginsenoside Rd<\/a><\/td> Ginsenoside Rd is a natural triterpenoid compound found in the roots of Panax ginseng C. A. Mey. <\/td><\/tr> 83480-64-2 <\/td> Ginsenoside Rd2<\/a><\/td> Ginsenoside Rd is a primary constituent of the ginseng rhizome and the administration of ginsenoside Rd significantly increased the reduced GSHPx and glutathione reductase activity. <\/td><\/tr> 52286-59-6 <\/td> Ginsenoside Re<\/a><\/td> Ginsenoside Re shows effective antidiabetic activities via significant antioxidant efficacy, particularly in the prevention of diabetic microvasculopathy. <\/td><\/tr> 52286-58-5 <\/td> Ginsenoside Rf<\/a><\/td> It inhibits Ca2+ channels in mammalian sensory neurons through a mechanism requiring G-proteins, whereas a variety of other ginsenosides were relatively ineffective. It might be useful in itself or as a template for designing additional modulators of neuronal Ca2+ channels. It induces G2\/M phase cell cycle arrest and apoptosis in human osteosarcoma MG-63 cells through the mitochondrial pathway. <\/td><\/tr> 22427-39-0 <\/td> Ginsenoside Rg1<\/a><\/td> Ginsenoside Rg1 protects against arthitis through osteoclast differentiation inhibition. Ginsenoside Rg1 exhibits anti-inflammatory and anticancer activities. <\/td><\/tr> 52286-74-5 <\/td> Ginsenoside Rg2<\/a><\/td> It has a neuroprotective effect against glutamate-induced neurotoxicity through mechanisms related to anti-oxidation and anti-apoptosis. It inhibits nicotinic acetylcholine receptor-mediated Na+ influx and channel activity. It might regulate the 5-HT3A receptors that are expressed in Xenopus oocytes. It may have properties that inhibit or prevent the growth of tumors. <\/td><\/tr> 14197-60-5 <\/td> Ginsenoside Rg3<\/a><\/td> It shows a synergistic antitumor effect with cisplatin in cisplatin-resistant bladder tumor cell lines. It possesses an ability to inhibit the lung metastasis of tumor cells, and the mechanism of their antimetastatic effect is related to inhibition of the adhesion and invasion of tumor cells, and also to anti-angiogenesis activity. <\/td><\/tr> 186763-78-0 <\/td> Ginsenoside Rg5<\/a><\/td> Ginsenoside Rg5, a main constituent isolated from red ginseng, exhibits anti-inflammatory property as in LPS-stimulated alveolar macrophages it inhibited the expression of proinflammatory cytokines including IL-1\u03b2 and TNF-\u03b1, as same as inflammatory enzyme <\/td><\/tr> 147419-93-0 <\/td> Ginsenoside Rg6<\/a><\/td> Ginsenoside Rg6, extracted from steamed notoginseng, exhibited significantly potent inhibitory effects on IL-12 p40 production in LPSstimulated BMDCs. <\/td><\/tr><\/tbody><\/table><\/div>\n
\nLeung K W. Ginseng pharmacology: Signaling pathways of ginsenoside-Rg1 in human umbilical vein endothelial cells[M]. HONG KONG BAPTIST UNIVERSITY (HONG KONG), 2006.<\/p>\n","protected":false},"excerpt":{"rendered":"