topoisomerase

What is Exatecan Mesylate?

What is Exatecan Mesylate?

Exatecan Mesylate is a semi-synthetic water-soluble derivative of camptothecin. It is a new type of topoisomerase I inhibitor with anti-tumor activity. The anhydrous, alkali-free form of the drug is called […]

Exatecan mesylate

Maintenance of DNA topology is critical for normal DNA replication, transcription and repair in eukaryotic cells. One family of enzymes, the topoisomerases, is essential for this process. Eukaryotic topoisomerase I […]