Nanotechnology is widely researched in anti drug-resistance, in one blog published days ago at this site the application of nanotechnology in slowing down the growth of tumor was discussed, which in nature is taking advantage of nanotech’s transferring ability and making drugs to battle with drug resistance. This blog furtherly talks about the employment of nanoparticles in anti drug resistance.
Chemists can now use nanotechnology to kill anti-drug bacteria by making drugs penetrate into the biofilm of bacteria and then destroy them. The drug will exist in the form of liquid drop, a mix of peppermint and cinnamon extracts.
Bacteria gathering to form the biofilm that can protect them and their activities inside,but much worse is that the biofilm is infectious and is the leading cause of several diseases like chronic wounds and various hospital infections. Besides the cluster of the bacteria is of high drug resistance.
Biofilm of bacteria comes into being when bacteria began to secrete a glutinous substance which will conglutinate other bacteria and form the biofilm. Most bacteria are with the ability to release such substance, thus one biofilm may contain many types of bacteria.
To kill the bacteria protected by biofilm requires the drug passing through the barrier then taking effects. Scientists have found a efficient way to solve the difficulties bringing by the film with nanotechnology. Water-like drug made of peppermint and cinnamon is placed in a ball, which is set inside of a silica nanoparticle.
But how can the silica nanoparticle go through the biofilm and release the drugs it carries? Scientists found that the bacteria biofilm is negatively charged. Thus if the silica parcticle can be positively charged, it will be easy for them to pass the film, which is accessible with the present technology.
After the particle go into biofilm, the silica shell will erode in the acidic environment and release the drug of peppermint and cinnamon, then function their ability to kill bacteria. Tests found that the drug made of peppermint and cinamon may kill up to three species of bacteria and the killing rate can be as high as 99.9% for every type that can be killed.
Nanotech brings accuracy to the sites needed to be treated, exempting many side effects caused by traditional therapy. What’s more is that it’s always with high efficiency in performance.
It’s very promising for the nanotechnology being widely applied in killing anti drug resistance bacteria, even cells with anti-drug properties as more and more positive research results are presented by scientists in the this area and it will be frequently used in cancer and the diseases with the character of frequent mutation.