2021 April

What is Exatecan Mesylate?

What is Exatecan Mesylate?

Exatecan Mesylate is a semi-synthetic water-soluble derivative of camptothecin. It is a new type of topoisomerase I inhibitor with anti-tumor activity. The anhydrous, alkali-free form of the drug is called […]

The Role of Pseudouridine in Malignant Tumors

The Role of Pseudouridine in Malignant Tumors

Pseudouridine (PU) is also called 5-ribosyluracil. Pseudouridine is a modified nucleoside and is an isomer of uridine. The connection method is that the 5-position carbon atom (C-5) on the heterocyclic […]

Pseudouridine in RNA

Pseudouridine in RNA

RNA not only acts as an intermediate or effector molecule in protein synthesis, but also has a direct functional effect on gene expression. Therefore, the importance of RNA modification has […]

Dosage Forms

Dosage Forms

1. What is “Pharmaceutics” Medicines are drug-delivery systems, which very rarely drugs alone but require additives (termed excipients) to make them into dosage forms. The word “pharmaceutics” is used in […]

Research of nucleosides

Research of nucleosides

Introducation Nucleosides, composing of a nucleobase (A, T, C, G or U) and a pentofuranose (ribose or 2-deoxyribose), are the fundamental units of the genetic material (DNA and RNA) for […]

New nanoparticle delivery platform breakthroughs the blood-brain barrier and brings hope to a variety of neurological diseases

New nanoparticle delivery platform breakthroughs the blood-brain barrier and brings hope to a variety of neurological diseases

The blood-brain barrier (BBB) refers to the barrier between blood plasma and brain cells formed by brain capillary walls and glial cells, and the barrier between plasma and cerebrospinal fluid […]