2019 December

Science Translational Medicine: Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

Science Translational Medicine: Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

In a new study, using advances in nanotechnology, researchers have found that restoring p53 not only delays the growth of p53-deficient liver and lung cancer cells, but may also make cancer drugs mTOR inhibitors […]

What are the functions of Rapamycin? (II)

What are the functions of Rapamycin? (II)

PLoS Biol: Scientists reveal new mechanism of Rapamycin. doi: 10.1371 / journal.pbio.3000252 Recently, in a research report published in PLoS Biology, scientists from the University of Michigan revealed a new […]

What are the functions of Rapamycin? (I)

What are the functions of Rapamycin? (I)

Rapamycin (RAPA), also known as “sirolimus”, was first discovered by scientists in the soil of Easter Island, Chile in 1975 due to its strong antifungal properties. Rapamycin is a macrolide […]

Durvalumab and Pabolizumab for lung cancer treatment

Durvalumab and Pabolizumab for lung cancer treatment

Small cell lung cancer (SCLC) is a rapidly developing, invasive lung cancer that accounts for about 15% of all lung cancer cases. Among them, about three-quarters of patients with small […]