2019 January

C&EN’s molecules of the year for 2018

C&EN’s molecules of the year for 2018

The US journal Chemical and Chemical News (C&EN) recently published its 2018 Molecular list. These molecules received a lot of attention in 2018. Let’s take a look at these attractive […]

EGFR-targeted Related Drugs

EGFR-targeted Related Drugs

Introduction of EGFR EGFR is the expression product of proto-oncogene C-ERBB1, the receptor of EGF cell proliferation and signal transduction. It is a member of epidermal growth factor receptor (HER) […]

Research and Development of Janus Kinase (JAK) Inhibitors

Introduction of JAK-STAT signaling Pathway The JAK-STAT signaling pathway is a signal transduction pathway stimulated by cytokines, which is involved in many important biological processes such as cell proliferation, differentiation, […]

FDA approved 3-4 heterocyclic oxygen drugs

FDA approved 3-4 heterocyclic oxygen drugs

Oxygen heterocyclic ring is one of the most common heterocyclic rings in drugs and natural products. By the end of 2017, 311 drug molecules had at least one oxygen heterocyclic […]