2016 February

Role of excipients in the crystallization of Albendazole Has Been Reported

Role of excipients in the crystallization of Albendazole Has Been Reported

Mihir K. Raval and coworkers reported cocrystallization of Albendazole. Cocrystallization approach with solvent evaporation technique at room temperature has been utilized to improve the physicochemical and mechanical properties of albendazole […]

Breakdown of Phosphatidylserine Asymmetry Following Treatment of Erythrocytes with Lumefantrine

Breakdown of Phosphatidylserine Asymmetry Following Treatment of Erythrocytes with Lumefantrine

Background: Lumefantrine, a commonly used antimalarial drug, inhibits hemozoin formation in parasites. Several other antimalarial substances counteract parasitemia by triggering suicidal death or eryptosis of infected erythrocytes. Eryptosis is characterized […]

Total synthesis of avermectin B1a revisited

Total synthesis of avermectin B1a revisited

Total synthesis of avermectin B1a revisited was achieved by Masahiro Hirama and co-workers in Tohoku University in Japan. Avermectins were isolated as compounds possessing anthelmintic activity from the culture broth of Streptomycesavermitilis by Ōmura […]