|Description||(±)-Blebbistatin is a selective inhibitor of myosin II ATPase. It reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.|
|Brife Description||myosin II ATPase inhibitor|
|Purity||≥98% by HPLC|
|Related CAS||1177356-70-5 (L-enantiomer)|
A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin’...
Omecamtiv mecarbil is a cardiac-specific myosin activator with an EC50 of 0.6 μM.
(+)-Blebbistatin is the inactive enantiomer of Blebbistatin, an inhibitor of myosin II ATPase. (+)-Blebbistatin can be used as a negative control of the active ...
(±)-Blebbistatin is a selective inhibitor of myosin II ATPase. It reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in verte...
ML-7 Hcl is a cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of myosin light chain kinase (Ki = 300 nM). It also inhibt smooth-mus...
MLCK inhibitor peptide 18
A myosin light chain kinase (MLCK) inhibitor (IC50= 50 nM), and inhibits CaM kinase IIonly at 4000-fold higher concentrations.
MYK-461 is a myosin inhibitor that selectively decreases the ATPase activity of cardiac myosin heavy chain, thus it is potentially for the treatment of hypertro...