|Description||Bindarit treatment inhibits the release of MCP-1 from IL-1 stimulated osteoblast cell line Saos-2.|
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM.
Domiphen bromide is a quaternary ammonium antiseptic with actions as a cationic surfactant.
A 438079 hydrochloride
A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell li...
Butyl 4-aminobenzoate acts as a long-duration local anesthetic. It aids in treatment of chronic pain. It is also known to induce anti-nociception effects in sub...
Ajmaline is an alkaloid which could extracted from Rauwolfia serpentina. It is an antiarrhythmic agent, acting through changing the shreshold and the shape of c...
Oxonic acid potassium salt
Oxonic acid potassium salt is an inhibitor of uricase. It has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss ...
Cysteamine is an agent for the treatment of nephropathic cystinosis and an antioxidant. It has been shown to increase intracellular glutathione levels in cystin...
STING agonist; Induces antitumor immunological responses
Importazole is a cell-permeable inhibitor of importin-β. Importazole specifically inhibits the function of importin-β, likely by altering its interaction with R...
S107 is a type 1 ryanodine receptor (RyR1) stabilizer that binds RyR1 and enhances the binding affinity of calstabin-1. S107 increased FKBP12 binding to RyR1 in...
Neuroblastoma, the most common solid extracranial neoplasm in children, originates from embryonic neural crest cells that usually form the sympathetic ganglia a...
A coronary vasodilator that does not require hepatic biotransformation
PLX-7683, a pyrrolopyridine derivative, has been found to be a paradox breaker that was studied to exhibit more durable efficacy and better safety than some for...
Dronedarone is a Class III antiarrhythmic and a multi-channel blocker for atrial fibrillation. It blocks potassium, sodium, and calcium channels and also exhibi...
Vitamin B12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
Bisegliptin is an antidiabetic agent, but no detailed information has been published yet.
A carcinogen as a a major metabolite of Nicotine in humans.
FR-202306 is a synthetic peptide deformylase (PDF) inhibitor.
CCF-642 is a protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of act...
5S rRNA modificator
5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to tha...