|Description||Bilastine is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.|
|Synonyms||Bilastine, trade name Bilaxten|
Zolantidine dimaleate is a potent brain penetrating histamine H2 receptor antagonist.
Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic r...
Halopyramine is known as a competitive reversible H1-receptor antagonist. It exerts its pharmacological action by competing with histamine for the H1 subtype hi...
A 987306 is a potent histamine H4 receptor antagonist (pKi = 8.24 and 8.47 in human and rat H4 receptors, respectively) with 162-, 620-, and > 1600-fold selecti...
Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.
Propiomazine Hydrochloride is an antihistamine blocking H1 receptors. It is used to treat insomnia and to produce drowsiness. It is also used to relieve anxiety...
JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other h...
FR-A 19 is a Histamine H2 receptor agonist with potent anti-allergic properties. It can inhibit IgE-mediated human basophil histamine release in a nanomolar ran...
Hydroxyzine pamoate, a derivative of hydroxyzine, is a histamine H1-receptor antagonist that has been used as anxiolytic and antihistaminic so that it is probab...
Chlorcyclizine hydrochloride (1:x)
The hydrochloride salt form of Chlorcyclizine which could be used as an antihistamine agent and is also found to have anticholinergic effect at some extent.
Impentamine dihydrobromide is the dihydrobromide salt of impentamine, which is a highly selective and the most potent histamine H3 antagonist with pA2 value of ...
Amthamine dihydrobromide is the dihydrobromide salt of amthamine, which is a highly selective histamine H2 receptor agonist. It is a weak antagonist at H3 and h...
Proxyfan oxalate is a high affinity histamine H3 receptor ligand (pKi = 8.62), acting as a protean agonist with activity ranges from full agonist to inverse ago...
ROS 234 dioxalate
ROS 234 dioxalate is a potent H3 antagonist (pKB at guinea-pig ileum H3-receptor = 9.46).
ICI 162,846 is a potent histamine H2 receptor antagonist.
Zaltidine is an effective but hepatotoxic H2-receptor antagonist. It has higher incidence of hepatic damage than with commonly used H2-receptor antagonists. It ...
GT 2016 is a high affinity and brain-penetrant histamine H3 receptor antagonist (Ki = 43.8 nM). It displays selectivity against H1 and H2 receptors (IC50 >10 μM...
KDM5A-IN-1, a pyrrolidine amide compound, is an inhibitor histone demethylases.
Dexbrompheniramine is an histamine H1-receptor antagonist used for the treatment of allergic conditions including hay fever or urticaria. It is the pharmacologi...
GSK-189,254 is a H3 histamine receptor inverse agonist. It has subnanomolar affinity for the H3 receptor with Ki of 0.2nM. It possesses stimulant and nootropic ...